| 摘要: |
| 目的：了解我院儿童药物不良反应（ADR）情况，为临床合理用药提供参考。方法：对我院2014年1月至12月上报的105份儿童药物ADR报告进行回顾性分析。结果：105例儿童ADR中，男80例（76.19%），女25例（23.81%）；以静脉给药者居多，占99例（94.29%）；抗感染药物引起的ADR居首位，涉及18种抗感染药物，共有34例，占总例数的32.38%；皮肤及其附件损害是ADR最主要的表现，共68例（64.76%）。结论：应加强儿童药物ADR监测，确保临床安全、有效、合理用药。 |
| 关键词: 药物不良反应 儿童 合理用药 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2016.02.015 |
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| 基金项目: |
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| Analysis of 105 Cases of Children Adverse Drug Reactions |
| Yang Zhi, Peng Cuiying, He Limei, Zhang Haixia, Li Jing, Long Rong, He Zhoukang |
| (Children's Hospital of Hunan Province，Hunan Changsha 410007, China) |
| Abstract: |
| Objectives: to investigate the occurrence of adverse drug reactions (ADR) in children so as to improve the rational drug use in the clinic. Methods: A total of 105 cases of ADRs in Hunan Children’s Hospital from January 2014 to December 2014 were retrospectively statistically analyzed. Results: Of the total 105 cases, 80 cases (76.19%) were male, and only 25 cases (23.81%) were female. Most of the cases were induced by intravenous injection, accounting for 99 cases (94.29%). 34 cases (32.81%) were induced by 18 kinds of antiinfective drugs, which were the first category of drugs to cause ADR. The injury of skin and its appendants was the most common ADR, which occupied 68 cases (64.76%). Conclusion: in order to ensure the safe, effective and rational administration of children in the clinic, the consciousness of ADR monitoring should be strengthened. |
| Key words: Adverse drug reaction Children Rational use of drugs |
