| 摘要: |
| 目的：探讨儿童普通肺炎支原体肺炎（MPP）急性期及恢复期肺通气功能的变化及其检测意义。方法：选取2014年6月至2015年6月在我院住院的5~14岁普通MPP急性期（发病1周内）患儿74例，行常规肺功能检测，随访至恢复期（发病后第3周），66例再次行常规肺功能检测；另选取同期健康儿童60例作为对照组。结果：普通MPP急性期各项肺功能指标（FVC、FEV1、PEF、FEF25、FEF50、FEF75、MMEF）与FEV1/FCV较恢复期均下降（P均<0.01）；恢复期FVC、FEV1、PEF基本恢复正常，而FEF25、FEF50、FEF75、MMEF较对照组仍有减低（P均<0.01）；急性期与恢复期FEV1/FVC均保持在正常范围。结论：儿童普通MPP急性期存在限制性、阻塞性通气功能障碍及小气道损害，限制性通气功能障碍相对较轻，小气道损害相对较重，而在恢复期限制性及阻塞性肺通气功能障碍明显改善，但仍有小气道损害，故普通MPP小气道损害时间明显较大气道长。肺通气功能检测可以较为客观地反映肺损害的情况，可以判断病情轻重、评估疗效及判断预后。 |
| 关键词: 肺功能 肺炎支原体 普通肺炎 儿童 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2016.11.002 |
|
| 基金项目: |
|
| Clinical Significance of Pulmonary Function Testing of Common Pneumonia Mycoplasma Pneumonia in Children |
| Wang Longhui, Ning Ning, Huang Xuehui, Ding Guobiao, Wu Xiaoling |
| (Jiujiang Maternal and Child Health Care Hospital, Jiangxi Province, Jiangxi Jiujiang 332000, China) |
| Abstract: |
| Objective: To discuss the changes of pulmonary ventilation function in children with common Mycoplasma pneumoniae pneumonia (MPP) during the acute phase and recovery phase and its clinical significance. Methods: 74 cases of 5-14 years old children in acute Mycoplasma pneumonia and 60 healthy children were monitored lung function test, and 66 children following up until recovery stage (the 3rd week after the onset) were monitored lung function test again.FVC, FEV1, PEF FEF25, FEF50, FEF75, MMEF actual value and expected value ratio, FEV1/FVC were detected in the test. Results: The pulmonary function index in the acute phase of Common MPP were lower than in the recovery phase, which FEF25, FEF50, FEF75, MMEF decreased obviously, while FEV1, FVC decreased slightly,there were statistical significant differences (P<0.05); FVC, FEV1, PEF recovered to normal level, while FEF25, FEF50, FEF75, MMEF in the recovery phase of common MPP were lower than the healthy controls, statistically significance were shown with the differences (P<0.05); FEV1/FVC kept in normal range during the acute phase and recovery phase. Conclusion: There were restrictive and obstructive ventilation dysfunction and small airway damage in the acute phase of common MPP, restrictive ventilation dysfunction relatively light, small airway damage relatively heavy; while restrictive and obstructive pulmonary ventilation dysfunction were significantly improved in recovery phase, small airway damage still existed. Therefore, it is obvious that the damage time in small airway is significantly longer than that of the large airway. |
| Key words: pulmonary function Mycoplasma pneumoniae common pneumonia children |
