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| 手足口病患儿红细胞功能变化及临床意义 |
| 潘智军,王兴民,傅锦坚,雷先强,张晶,易容松,李艳,莫胜福,韦兴高 |
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| (广西柳州市妇幼保健院,广西柳州 545001) |
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| 摘要: |
| 目的:探讨手足口病对红细胞功能的影响。方法:收集2014年在我院住院的手足口病患儿,按照病情分组,行红细胞、血清铁和血气分析检测。结果:随着手足口病病情的加重,血液中红细胞数目、红细胞平均体积和血红蛋白含量有增加的趋势(P>0.05),血清铁含量也从1期的(5.60±4.18）μmol/L增加到4期的（13.13±4.70）μmol/L。同时,PaO2由1期的(91.30±19.50)mm Hg下降到4期的(80.71±27.57)mm Hg;pH由1期的7.41±0.04下降到4期的7.33±0.19;PaCO2由1期的(31.40±4.32)mm Hg增加到4期的(36.43±19.03) mm Hg;血乳酸含量由1期的(1.47±0.90) mmol/L增加到4期的(3.67±3.10)mmol/L。结论:红细胞可能参与了手足口病的发生发展,随着手足口病病情的加重,红细胞铁利用和携氧功能障碍也加重。 |
| 关键词: 手足口病 儿童 红细胞 携氧功能 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2016.10.001 |
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| 基金项目:广西壮族自治区科学基金,编号Z2014375。 |
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| Clinical Significance of Red Blood Cell Function Change in Children with Hand-Foot-Mouth Disease |
| Pan Zhijun, Wang Xingmin, Fu Jinjian, Lei Xianqiang, Zhang Jing, Yi Rongsong, Li Yan, Mo Shengfu, Wei Xinggao |
| (Liuzhou Maternal and Child Health Hospital, Guangxi Liuzhou 545001, China) |
| Abstract: |
| Objective: To investigate the change of red blood cell function in children with hand-foot-mouth disease. Methods: Children with hand-foot-mouth disease, admitted by our hospital from January 2014 to December 2014, were divided according to the condition. Erythrocyte, serum iron and blood gas were detected. Results: Erythrocyte count, mean corpuscular volume and hemoglobin level increased with illness aggravating and serum iron also increased from (5.60±4.18）μmol/L in stage 1 to (13.13±4.70）μmol/L in stage 4. Meanwhile, PaCO2 and blood lactic acid were respectively raised from (31.40±4.32) mm Hg and (1.47±0.90) mmol/L in stage 1 to (36.43±19.03) mm Hg and (3.67±3.10) mmol/L in stage 4, but PO2 and pH value decreased (91.30±19.50) mm Hg and 7.42±0.04 in stage 1 to (80.71±27.57) mm Hg and 7.33±0.19 in stage 4. Conclusion: Erythrocyte might participate in the genesis and development of hand-foot-mouth disease. The oxygen carrying function and iron utilization function are also injury with illness aggravating. |
| Key words: hand-foot-mouth disease children erythrocyte oxygen carrying function |
