| 摘要: |
| 目的:对儿童使用抗感染药物发生不良反应(ADR)的规律和特点进行探讨,为临床药物使用提供参考。方法:收集我院2013-2016年105例患儿抗感染药物引起的ADR报告,分别从患儿基本信息、ADR临床表现、药物种类等多方面探讨原因,并提出针对性的预防措施。结果:静脉给药易发生ADR;药物中以头孢菌素类所致ADR较多;ADR累及器官主要集中在皮肤及附件损害。结论:儿童在临床中使用抗感染药物时更应警惕ADR。 |
| 关键词: 儿童 抗感染药物 不良反应 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2018.01.016 |
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| 基金项目: |
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| Evaluation of Adverse Reactions Caused by Anti-Infectives in Our Hospital from 2013 to 2016 |
| Li Shasha, Xu Jiping, Liu Shuai, Li Jun |
| (Shandong Provincial Hospital Affiliated to Shandong University, Shandong Jinan 250000, China) |
| Abstract: |
| Objective: To investigate the characteristics and rules of the adverse reactions caused by anti-infectives among children and provide references for clinical drug use. Methods: The study was made to collect the 105 case reports of adverse reactions caused by anti-infectives in our hospital from 2013 to 2016. The reasons from the children's information, ADR clinical manifestations, the drug kinds were analyzed, and putted forward relevant preventive measures. Results: Intravenous infusion was easy to cause adverse reactions. Most cases of ADR were caused by cephalosporins. The common manifestation was skin and accessory damage. Conclusion: The clinical application of antibiotics should pay more attention to adverse reaction. |
| Key words: children anti-infectives adverse reactions |
