| 摘要: |
| 病毒性脑炎(viralSencephalitis,VE)是一种常见的小儿中枢神经系统感染性疾病,儿童发病率约6.6-18.4/10万[1],是病毒侵犯脑实质引起的脑组织炎症病变及脱髓鞘改变。在急性期,由于脑细胞坏死、炎症浸润等损伤神经元出现癫痫发作。急性期后,病变部位可能留下永久的病灶,反复出现癫痫发作,继发“脑炎后癫痫”(Postencephalitic epilepsy PEE),其发生率约4-20%[3.4],是影响病毒性脑炎预后的重要因素之一。本文旨在对VE相关癫痫发作及继发癫痫进行综述,以便能更好了解VE相关癫痫的特点及其危险因素。 |
| 关键词: 病毒性脑炎 脑炎后癫痫 癫痫 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2018.07.016 |
| 投稿时间：2017-02-04修订日期：2017-03-02 |
| 基金项目: |
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| Viral Encephalitis and Epilepsy |
| Zhang Jia, Jiang Li |
| (Children’s Hospital of Chongqing, Chongqing 400014, China) |
| Abstract: |
| Viral encephalitis(VE) is a common pediatric infectious disease of the central nervous system and incidence of about 6.6-18.4/100000 [1], is the virus infringe the brain tissue and caused inflammation lesions and demyelinating changes. In the acute stage, due to damage neurons appear such as brain cell necrosis, inflammatory infiltration et al,and cause epileptic seizures. After the acute phase, It leave the pathological changes may be permanent, recurring seizures, name secondary epilepsy，Postencephalitic epilepsy(PEE), the incidence of about 4-20% [3.4], is one of the important factors influencing the prognosis of viral encephalitis. This paper aimed to overview VE related seizures and Postencephalitic epilepsy ,in order to better understand the VE related characteristics and risk factors. |
| Key words: viral encephalitis,postencephalitic epilepsy,epilepsy |
