| 摘要: |
| 目的:探讨临床药师在药物性肝损害因果分析及治疗中的作用。方法:临床药师参与1例赖氨匹林注射液致严重药物性肝损害的治疗过程,运用Roussel Uclaf因果关系评价法对肝损害与赖氨匹林的因果关系进行评估,根据相关文献与临床医师共同制定个体化给药方案。结果:临床药师参与治疗后,患儿肝功能生化指标明显下降,病情得到控制。结论:临床药师为患者提供个体化药学服务,有利于促进临床用药安全、合理。 |
| 关键词: 赖氨匹林 不良反应 药物性肝损害 Roussel Uclaf因果关系评价法 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2018.01.014 |
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| 基金项目: |
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| Clinical Pharmacist Apply Roussel Uclaf Causality Assessment Method to Join in a Case of Children Severe Liver Injury Caused By Aspirin-DL-Lysine |
| Peng Min, Deng Nan, Deng Yinhua |
| (Hunan Provincial People's Hospital, Hunan Changsha 410005, China) |
| Abstract: |
| Objective: To discuss the role of clinical pharmacists in the cause analysis and treatment of drug-induced liver injury. Methods: Clinical pharmacists participated in the treatment process of severe drug-induced liver injury. The causal relationship of liver damage and the aspirin-DL-lysine was evaluated by the amount of Roussel Uclaf causality assessment method scale. According to the related literature, the individualized drug delivery scheme was formulated by clinical pharmacists and clinicists. Results: The children's biochemical indexes of liver function decreased obviously, and the condition of the disease was controlled after clinical pharmacists participated in the treatment. Conclusion: Individualized pharmaceutical care for patients provided by clinical pharmacists is conducive to the promotion of safe and rational clinical medication. |
| Key words: aspirin-DL-lysine adverse reactions drug-induced liver injury Roussel Uclaf causality assessment method |
