| 摘要: |
| 目的:了解我院儿科住院患儿的超说明书用药情况,为规范儿童超说明书用药、促进儿童安全合理用药提供参考。方法:利用电子病历系统从我院2016年12月至2017年2月1 279份儿科住院病历中抽取104份(8.13%),收集患儿的基本信息,审核病历中的用药医嘱,依据药品说明书及药学知识判断是否超说明书用药,并对超说明书用药类型等情况进行统计分析。结果:104份病历共包含用药医嘱1 739 条,涉及18类81种药品,其中超说明书用药医嘱412条(23.69%),涉及药品类别主要为抗病毒药、维生素和矿物质、呼吸系统用药;超说明书用药类型前3 位依次为超剂量(33.98%)、超适应人群(25.24%)、超适应年龄(19.42%)。结论:我院儿科住院医嘱存在超说明书用药情况,应逐步完善说明书儿童用药信息,加强超说明书用药的监管,以促进儿童安全合理用药。 |
| 关键词: 超说明书用药 儿科 住院 医嘱 合理用药 |
| DOI：doi: 10.13407/j.cnki.jpp.1672-108X.2017.12.015 |
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| 基金项目: |
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| Investigation and Analysis of Off-Label Drug Use in Pediatric Inpatient of Our Hospital |
| Zhi Wenyu, Zhang Guifen, Tang Hu |
| (Changshu First People's Hospital, Changshu Hospital Affiliated to Soochow University, Jiangsu Changshu 215500, China) |
| Abstract: |
| Objective: To understand the off-label drug use in the pediatric inpatient cases in our hospital, promote children's medication safety and provide the basis for normalizing the off-label drug use. Methods: One hundred and four inpatient cases (8.13%) were randomly selected in the pediatric inpatients from December 2016 to February 2017. The children's basic information was retrieved from the electronic medical records system. The admission notes were referred to and the medication orders were reviewed
in order to determine whether off-label drug use based on drug instructions and pharmaceutical knowledge. The type and quantity of off-label drug use were statistically analyzed. Results: One hundred and four inpatient cases included 1,739 medical orders and involved 18 categories and 81 kinds of drugs. There were 412 off-label drug use orders (23. 69%). In the off-label drug use, antiviral drugs, vitamins and mineral substance and respiratory drugs were mostly. The proportions of the overdosage, the superfit population, and superfit age of administration were the top 3 (33.98%, 25.24% and 19.42%). Conclusion: There are off-label drug uses in pediatric inpatient medical orders. We shall gradually improve the instructions for children爷s medication information, strengthen the supervision and management of the use of drugs and promote safe and rational use of drugs in pediatrics. |
| Key words: off-label drug use pediatric inpatient medical order rational use of drugs |
