| 摘要: |
| 草铵膦是目前农业中广泛使用的一种除草剂,其作用靶点是谷氨酰胺合成酶(GS)。草铵膦不仅抑制植物体内GS致其死亡,同样可对动物体内的GS不可逆抑制并破坏其后GS相关过程,对其氮代谢造成影响,但人类服用草铵膦后的中毒解救目前在国内未见文献报道。本文报道我院收治的1例草铵膦中毒患儿的治疗过程,药师作为治疗团队中的一员,协助医师救治患儿并进行药学监护。 |
| 关键词: 草铵膦 临床药师 药学监护 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2018.11.012 |
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| 基金项目: |
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| Treatment and Pharmaceutical Care for Children with Acute Poisoning of Glufosinate-Ammonium |
| Yang Mei, Wang Xiaoling, Qian Suyun |
| (Children's National Medical Center, Beijing Children's Hospital Affiliated to Capital Medical University, Beijing 100045, China) |
| Abstract: |
| Glufosinate-ammonium is a herbicide that widely used in agriculture, and its target is glutamine synthetase (GS). Glufosinate-ammonium not only kills plants by inhibiting GS, but irreversibly inhibits GS in animals and destroys the subsequent GS-related processes, which affects its nitrogen metabolism. However, the poisoning rescue for humans taking glufosinate-ammonium had never been reported in literature from China. This article reported the therapeutic process of a child with glufosinate-ammonium poisoning admitted into our hospital. As a member of the treatment team, the pharmacists assisted the physicians in rescuing the child and performed pharmaceutical care. |
| Key words: glufosinate-ammonium clincal pharmacists pharmaceutical care |
