| 摘要: |
| 目的：探讨糠酸莫米松鼻喷雾剂联合鼻渊通窍颗粒治疗儿童腺样体肥大的疗效。方法：将120例4~12岁腺样体肥大的儿童随机分成对照组和观察组各60例，对照组采用糠酸莫米松鼻喷雾剂喷鼻和口服桉柠蒎肠溶软胶囊6周，观察组在对照组基础上加用鼻渊通窍颗粒，比较两组患儿治疗前后的临床症状评分及腺样体大小的变化情况。结果：治疗后，观察组鼻塞、流涕、打鼾评分及总分均低于对照组，差异均有统计学意义（均P<0.05）。治疗后两组患儿鼻塞、流涕、打鼾及总分较同组治疗前同类别评分均下降，差异有统计学意义（均P<0.05）。治疗后观察组患儿腺样体明显小于对照组，差异有统计学意义（P<0.05）；两组患儿治疗前后比较，腺样体均有不同程度的减小，差异均有统计学意义（P均<0.05）。结论：糠酸莫米松鼻喷雾剂联合鼻渊通窍颗粒治疗儿童腺样体肥大疗效好，是治疗腺样体肥大的理想中成药，值得临床推广。 |
| 关键词: 糠酸莫米松 鼻渊通窍颗粒 腺样体肥大 儿童 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2019.01.007 |
|
| 基金项目: |
|
| Nasal Spray Hormone and Biyuan Tongqiao Particles in the Treatment of Adenoid Hypertrophy in Children |
| Ding Feng1, Wang Ranran2, Xu Baoli3, Liu Yan1, Xiao Xiangli2, Huang Ying |
| (1. Hankou Hospital of Wuhan, Hubei Wuhan 430012, China; 2. Wuhan Red Cross Hospital, Hubei Wuhan 430015, China; 3. Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Wuhan 430022, China) |
| Abstract: |
| Objective: To investigate the effect of mometasone furoate nasal spray combined with Biyuan Tongqiao particles in the treatment of adenoid hypertrophy in children. Methods: A total of 120 children aged 4-12 years completed 6 weeks treatment were enrolled in a prospective and randomized controlled study. The children were randomly divided into two groups, the control group with mometasone furoate nasal spray and eucalyptol limonene and pinene enteric soft capsules, the observation group with Biyuan Tongqiao particles more than the control group. The clinical symptom scores and the changes of adenoid size were compared between the two groups before and after treatment. Results: The scores of nasal obstruction, rhinorrhea, snoring and total score in the two groups were lower than those before treatment (P<0.05). There was no significant difference between the observation group and the control group before treatment (P>0.05). After treatment, the scores of the observation group were lower than those of the control group, the difference was statistically significant(P<0.05). The relative ratio of adenoid to nasal posterior diameter, there was no significant difference between the two groups before treatment (P>0.05), but after the treatment, the difference between the two groups was statistically significant (P<0.05). Conclusion: Mometasone furoate appeats to be effective in treating children with adenoid hypertrophy, combined with the Biyuan Tongqiao particles can further improve the efficacy |
| Key words: mometasone furoate Biyuan Tongqiao particles adenoid hypertrophy children |
