| 摘要: |
| 目的:分析儿童房性心动过速的药物疗效及预后。方法:选择重庆医科大学附属儿童医院2005-2016 年收治的接受抗
心律失常药物治疗的109 例房性心动过速患儿临床资料,分为器质性心脏病组(先天性心脏病、心肌病、心肌炎)及无器质性心
脏病组,回顾性分析不同疾病组的抗心律失常药物疗效和随访情况。结果:109 例患儿中男62 例,女47 例,发病年龄0-13.4 岁。
心肌炎组洋地黄、β受体阻滞剂治疗总有效率最高,无器质性心脏病组以洋地黄治疗的总有效率最高。先天性心脏病组、心肌
病组的各药物疗效比较差异无统计学意义(P>0.05)。有完整随访资料的患儿47 例,随访时间10-73(32.4±15.3)个月,心肌
炎组、无器质性心脏病组的总有效率较高,<3 岁组患儿总有效率高于逸3 岁的患儿,差异有统计学意义(P<0.01)。3 例药物疗
效欠佳的房性心动过速患儿行射频消融术均得到有效控制。结论:房性心动过速无器质性心脏病患儿应用洋地黄的疗效较好,
心肌炎患儿洋地黄、β受体阻滞剂的疗效较好;绝大部分房性心动过速药物治疗最终预后良好,其中以心肌炎、无器质性心脏病
及小年龄组患儿更佳;药物疗效不佳者建议行射频消融术。 |
| 关键词: 房性心动过速 儿童 药物疗效 预后 |
| DOI：10.13407/j.cnki.jpp.1672-108X.2019.03.005 |
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| 基金项目: |
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| Drug Efficacy and Prognosis of Atrial Tachycardia in Children |
| Chen Si, Zhong Jiarong |
| (Lijia Branch of Affiliated Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China) |
| Abstract: |
| Objective: To investigate and analyze the drug efficacy and prognosis of atrial tachycardia in children. Methods: Clinical
data of 109 cases of atrial tachycardia treated with antiarrhythmic drugs in Children's Hospital of Chongqing Medical University from 2005 to 2016 were selected and divided into the organic heart disease group (congenital heart disease, cardiomyopathy, myocarditis) and the non-organic heart disease group. The efficacy and follow-up of antiarrhythmic drugs in different disease groups were analyzed retrospectively. Results: Among the 109 cases, 62 were male and 47 were female, and the age of onset was 13. 4 years old. In the myocarditis group, digitalis and β-blockers were the most effective, and the total effective rate of digitalis was the highest in the non-organic heart disease group. There was no significant difference in the efficacy between the congenital heart disease group and the cardiomyopathy group (P>0.05). There were 47 children with complete follow-up data. The follow-up time was from 10 to 73 (32.4±15.3) months. The total effective rate was higher in the myocarditis group and the non-organic heart disease group. The total effective rate was higher in the < 3 year old group than that in children ≥3 years old, the difference was statistically significant (P<0. 01).Three cases of atrial tachycardia were effectively controlled by radiofrequency ablation. Conclusion: The clinical efficacy of digitalis in children with atrial tachycardia without organic heart disease is the best, digitalis and β-blockers were the most effective in children with myocarditis. Most of the patients with atrial tachycardia had better prognosis, especially those with myocarditis, non-organic heart disease and small age group. Radiofrequency ablation is recommended for patients with poor efficacy. |
| Key words: atrial tachycardia children drug efficacy prognosis |
