| 摘要: |
| [摘要]目的：探讨家庭雾化治疗婴幼儿毛细支气管炎的临床疗效及预后。方法：148例婴幼儿毛细支气管炎患者，观察组（79例）采用家庭雾化治疗，对照组（69例）为住院治疗，两组均采用相同的综合治疗方法，包括呼吸道管理、止咳、化痰、口服孟鲁司特28 d等对症治疗，抗病毒（雾化吸入重组人干扰素a-1b）、雾化吸入糖皮质激素(布地奈德)和β2受体激动剂(特布他林)，2次/d，在治疗前5 d内每天复诊、评估病情，连续用药7 d。观察两组临床症状改善情况及临床疗效，1个月后随访肺功能。结果：观察组临床疗效总有效率（92.4%）优于对照组（81.2%），两组比较差异有统计学意义（χ2=4.163，P<0.05）；全身激素使用率、抗菌素使用率、静脉输液率、总医疗费用两组比较差异均有统计学意义（P<0.01）；1月后随访肺功能，潮气量两组比较差异无统计学意义（t=1.433，P>0.05）；达峰时间、达峰容积两组比较差异均有统计学意义（P<0.05）。结论：轻症毛细支气管炎，可采用家庭雾化的方式治疗，有利于快速控制患儿症状，取得了良好的疗效及社会效益、经济效益。 |
| 关键词: 家庭雾化 轻症 毛细支气管炎 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2019.09.009 |
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| 基金项目: |
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| Family Aerosol Inhalation in the Treatment of Bronchiolitis |
| Li Yao, Xie Lu, Ma Xiujuan, Liu Yu |
| (Kunming City Maternal and Child Health Hospital, Yunnan Kunming 650031, China) |
| Abstract: |
| [Abstract] Objective: To probe into the clinical efficacy and prognosis of family aerosol inhalation in the treatment of bronchiolitis. Methods: A total of 148 infants with bronchiolitis were enrolled, the observation group (n=79) was treated with family aerosol inhalation, while the control group (n=69) was hospitalized. Both groups were treated with the same comprehensive treatment methods, including respiratory tract management, cough relieving, phlegm resolving, oral montelulast for 28 d and other symptomatic treatment, antiviral (aerosol inhalation of recombinant human interferon α-1b), aerosol inhalation of corticosteroid (budesonide) and β2 receptor agonist (terbutaline), 2 times/d. Within 5 d before treatment, the patient was re-examined and evaluated every day. All patients received continuous medication for 7 d. The clinical symptoms and efficacy of two groups were observed. The lung function was followed up after 1 month. Results: The total effective rate of the observation group (92.4%) was better than that of the control group (81.2%), and the difference was statistically significant (χ2=4.163, P<0.05). There were statistically significant differences in the utilization rate of systemic hormones, antibiotics, intravenous infusion rate and total medical expenses between two groups (P<0.01). There was no significant difference in tidal volume between two groups after 1 month (t=1.433, P>0.05). There were significant differences between two groups in peak time and peak volume (P<0.05). Conclusion: Mild bronchiolitis can be treated by family aerosol inhalation, which is beneficial to quickly control the symptoms of children, and achieve better social benefits and economic benefits. |
| Key words: family aerosol inhalation mild bronchiolitis |
