| 摘要: |
| 目的：研究血清维生素A水平缺乏对儿童反复呼吸道感染、急性支气管肺炎和手足口病的影响及相关性分析。方法：2 200例儿童纳入研究，分为反复呼吸道感染（RRI）组、支气管肺炎（BP）组、手足口病（HFMD）组及对照组（同期门诊体检的健康儿童）。观察比较4组儿童的形态学以及检测血清维生素A（VA）的浓度水平变化。结果：4组儿童在一般资料比较差异无统计学意义（P>0.05）；男童血清VA水平为（0.27±0.12）mg/L，女童为（0.26±0.12）mg/L，差异无统计学意义（t=1.95，P>0.05）；三组病例组中亚临床维生素A缺乏(SVAD)、边缘型维生素A缺乏（MVAD）总检出率分别为40.00%、39.51%，均明显高于对照组的1.96%、20.36%，差异有统计学意义（P<0.05）；城市和农村患儿VAD及SVAD患病率比较差异无统计学意义（P>0.05）；不同年龄组VAD、SVAD及MVAD比较差异有统计学意义（P<0.05）。结论：维生素A与儿童感染性疾病关系密切，儿童反复呼吸道感染、支气管肺炎和手足口病患儿中普遍存在维生素A缺乏。 |
| 关键词: 维生素A 亚临床缺乏 反复呼吸道感染 支气管肺炎 手足口病 |
| DOI： |
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| 基金项目:国家卫生计生委专项基金,编号W2015EAE05 |
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| The Study of the Correlation between Vitamin A Levels and Infectious Diseases in Children |
| Li Yanqi, Wang Lijun, Feng Zhanwei |
| (Xi’an Children’s Hospital,) |
| Abstract: |
| objective: To study the effects of serum vitamin A deficiency in children with recurrent respiratory tract infections,acute bronchial pneumonia and hand-foot-mouth disease. Methods: In all of 2,200 cases, the patients were divided into recurrent respiratory tract infection (RRI) group, bronchial pneumonia (BP) group, hand-foot-mouth disease (HFMD) group and control group. The morphology of the three groups of children and the changes in serum levels of vitamin A were observed. Results: There was no statistically significant difference in the general morphology (age, sex, height, weight, residence) of the four groups (P>0.05). There was no statistically significant difference between serum VA level of boys and girls in all cases (P>0.05). The differences in serum vitamin A concentration were statistically significant (P<0.05). The total detection rate of VAD and SVAD in three groups was significantly higher than the control group, and the difference was statistically significant (P<0.05). Condusion: Vitamin A is closely related to infection diseases in children. Vitamin A deficiency is common in children with recurrent respiratory tract infections, bronchial pneumonia and hand-foot-mouth disease. The vitamin A deficiency of chronic infections (recurrent respiratory tract infections) were more obvious than acute infections(Bronchial pneumonia)． |
| Key words: vitamin A subclinical deficiency recurrent respiratory tract infections bronchial pneumonia hand-foot-mouth disease |
