| 摘要: |
| 目的:了解中药注射剂在儿童患者中超说明书用药现状与特点,为我院儿童住院患者中药注射剂合理用药提供参考。方法:回顾性随机抽取我院2016年7月1日至2017年6月30日儿童住院患者1 000例,依据药品说明书和相关文献,分析患者中药注射剂用药是否存在超说明书现象。结果:1 000例住院患者中药注射剂医嘱2 301条,超说明书用药医嘱1 343条,超说明书用药医嘱比例为58.37%,涉及使用药品7种。1 000例患儿中,中药注射剂超说明书用药为594例,比例为59.40%。结论:我院中药注射剂在儿童住院患者中普遍存在超说明书用药情况,多数中药注射剂的说明书中儿童用药信息缺乏,故应进一步的规范中药注射剂说明书中儿童的用法用量,杜绝不必要的超说明书用药。呼吁国家相关部门采取相应措施对超说明书用药现象进行监督管理。 |
| 关键词: 超说明书用药 中药注射剂 儿童住院患者 |
| DOI：10.13407/j.cnki.jpp.1672-108X.2019.06.014 |
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| 基金项目: |
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| Off-Label Use of Traditional Chinese Medicine Injection in Pediatric Inpatients from Our Hospital |
| Li Xiuyan, Miao Qiuli, Fan Hao, Zhang Yongkai |
| (The First Hospital of Jilin University, Jilin Changchun 130021, China) |
| Abstract: |
| Objective: To investigate the current status and characteristics of off-label use of traditional Chinese medicine injection in
children, so as to provide reference for rational use of traditional Chinese medicine injection in pediatric inpatients from our hospital. Methods: Totally 1,000 children hospitalized in our hospital from Jul.1st , 2016, to Jun.30th , 2017 were randomly selected. According to the drug instructions and relevant literature, the phenomenon of off-label use of traditional Chinese medicine injection was analyzed. Results: Among the 1,000 inpatients, there were 2,301 prescriptions for traditional Chinese medicine injection and 1,343 prescriptions for off-label drug use, and the incidence of off-label drug use was 58.37%, involving 7 kinds of drugs, these drugs all had off-label drug use to different degree. Among the 1,000 children, 594 were treated with off-label use of traditional Chinese medicine injection, and the incidence was 59.40%. Conclusion: Off-label drug use is common in the use of traditional Chinese medicine injection in pediatric inpatients from our hospital, and most of the traditional Chinese medicine injection is short of the drug information for children, therefore, the usage and dosage of children in the instruction of traditional Chinese medicine injection should be further standardized to prevent unnecessary off-label drug use. The relevant legislative departments of the state should take corresponding measures to supervise and manage this phenomenon. |
| Key words: off-label drug use traditional Chinese medicine injection pediatric inpatients |
