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威海市文登区359例婴幼儿维生素A营养状况分析
董崇娟1,王永强1,杨志敏1,王昭霞1,武静2,刘少璐1
0
(1.威海市中心医院,山东威海 264400;2.泰安市妇幼保健院,山东泰安 271000)
摘要:
目的:调查山东省威海市文登区0~3岁婴幼儿维生素A(VA)的营养状况。方法:选择2015年1月至2016年5月在威海市中心医院儿科呼吸门诊就诊和儿保门诊健康查体的359例婴幼儿(0~3岁),抽取静脉血2 mL,采用高效液相色谱串联质谱法测定血清VA含量,并填写家长调查问卷。结果:359例婴幼儿中,VA缺乏65例(18.11%),边缘型VA缺乏162例(45.13%),VA在正常范围132例(36.77%)。≤1岁组婴幼儿VA水平最低,>1~2岁组次之,>2~3岁组VA水平最高(P<0.05)。不同喂养方式下婴幼儿血清VA水平比较差异无统计学意义(P>0.05)。补充鱼肝油的婴幼儿血清VA水平高于未补充鱼肝油的婴幼儿(P<0.05)。呼吸道感染患儿血清VA水平低于健康婴幼儿(P<0.05)。结论:山东省威海市文登区0~3岁婴幼儿VA缺乏较为普遍,其中1岁内婴儿、呼吸道感染患儿是VAD高危群体,需要引起家庭、社会和医疗机构的高度重视。
关键词:  婴幼儿  维生素A  呼吸道感染
DOI:doi:10.13407/ j.cnki.jpp.1672-108X.2019.05.004
基金项目:国家卫生计生委医药卫生科技发展研究中心计划项目,编号W2015EAE087;威海市科技发展计划项目,编号2016GNS030鄄3。
Nutritional Status of Vitamin A in 359 Infants in Weihai Wendeng District
Dong Chongjuan1, Wang Yongqiang1, Yang Zhimin1, Wang Zhaoxia1, Wu Jing2, Liu Shaolu1
(1. Weihai Central Hospital, Shandong Weihai 264400, China; 2. Tai’an Maternal and Child Health-Care Hospital, Shandong Tai’an 271000, China)
Abstract:
Objective: To investigate the nutritional status of vitamin A (VA) in infants aged from 0 to 3 years old in Weihai Wendeng district. Methods: From Jan. 2015 to May 2016, 359 infants ( from 0 to 3 years old) admitted to the pediatric respiratory outpatient department of Weihai Central Hospital and the paediatric health care outpatient department for physical examination were selected, and 2 mL venous blood was taken. The serum VA content was determined by high performance liquid chromatography-tandem mass spectrometry, and the parent questionnaire was filled out. Results: Among the 359 infants, there were 65 cases of VA deficiency (18.11%), 162 cases of borderline VA deficiency (45.13%), and 132 cases of normal VA level (36.77%). The serum VA level of infants in the ≤1 years old group was the lowest, followed by the >1 to 2 years old group, and the serum VA level was the highest in the >2 to 3 years old group (P<0.05). There was no statistically significant difference in serum VA level of infants with different feeding patterns (P>0.05). The serum VA level of infants supplemented with cod liver oil was higher than that of infants without cod liver oil (P<0.05). The serum VA level was lower in infants with respiratory infection than in healthy infants (P<0.05). Conclusion: VA deficiency is relatively common in infants aged from 0 to 3 years old in Weihai Wendeng district, infants within 1 year old and respiratory infection are high-risk groups of VA deficiency, which need to be highly valued by families, society and medical institutions.
Key words:  infants  vitamin A  respiratory infection

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