| 摘要: |
| 目的：观察肺炎支原体肺炎（MPP）患儿胸片改变为节段性肺炎或支气管肺炎时的年龄、发热天数、外周血WBC、血清C反应蛋白（CRP）及血清肺炎支原体抗体滴度（MP-IgG）变化情况。方法：我院收治的219例MPP患儿根据胸片改变情况分为节段性肺炎组和支气管肺炎组，检测两组患儿WBC、CRP及MPIGG滴度指标。结果：219例MPP患儿中，节段性肺炎组65例（29.6％），平均年龄（93.83±53.11）月，支气管肺炎组154例（70.4％），平均年龄（55.06±38.60）月（P<0.05）；节段性肺炎组入组时平均发热天数（3.03±2.63）d，支气管肺炎组（2.01±2.00）d（P<0.05）；节段性肺炎组血清MP-IgG≥640的例数多于支气管肺炎组（P<0.05）；节段性肺炎组血清CRP值高于支气管肺炎组（P<0.05）。结论：MP感染后肺部炎症表现为节段性肺炎的患儿年龄偏大、发热天数较长、血CRP水平和MPIGG滴度更高，提示患儿全身炎症反应强烈，年长儿童MP感染后易发生严重肺部病变。 |
| 关键词: 肺炎支原体 抗体 节段性肺炎 C反应蛋白 儿童 |
| DOI：doi:10.13407/j.cnki.jpp.1672.108X.2019.07.001 |
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| 基金项目: |
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| Changes of Mycoplasma Pneumoniae Antibody Titer and C-Reactive Protein with Mycoplasma Pneumoniae Pneumonia |
| Wen Xiaobing, Liu Li, Tao Shuhang, Xiang Ling |
| (The Second People's Hospital of Chengdu) |
| Abstract: |
| Objective: To evaluate the difference of clinical features in children with Mycoplasma pneumoniae (MP), according to their chest radiographic patterns. Methods: A total of 219 children with MPP were divided into segmental pneumonia group and bronchopneumonia group according to the changes of chest X-ray. WBC, C-reactive protein (CRP) and MP-IgG titer were detected at the beginning of admission. Results: Among the 219 patients with MP, there were 65 (29.6%) segmental pneumonia cases and 154 (70.4%) bronchopneumonia cases. The patients with segmental pneumonia were older compared with those with bronchopneumonia (93.83±53.11 months vs. 55.06±38.60 months (P<0.05). The duration of fever in segmental pneumonia group was longer than that in the group with bronchial pneumonia (3.03±2.63 days vs. 2.01±2.00 days, P<0.05). The serum CRP value in the segmental pneumonia group was significantly higher than that in the bronchopneumonia group (P<0.05). Segmental pneumonia group had more cases with MP-IgG ≥640 than bronchial pneumonia group (P<0.05). Conclusion: Patients with segmental pneumonia after MP infection were older and had longer fever duration and had higher blood CRP and MP-IgG titer, suggesting a strong systemic inflammatory response. Older children with MP infection are prone to severe lung lesions. |
| Key words: Mycoplasma pneumoniae antibody segmental pneumonia C-reactive protein children |
