| 摘要: |
| 目的：评估重庆医科大学附属第二医院产科孕妇孕晚期维生素A（vitamin A，VA）的营养状况，针对我院孕妇孕期VA的营养状况提出合理建议。方法：以2016年9月至2017年1月期间孕晚期在重庆医科大学附属第二医院产科做产前检查的孕妇332人为调查对象，采用问卷调查、24 h膳食调查法了解孕妇膳食结构组成，通过高效液相色谱明确血清中视黄醇生成水平，采用VA每日推荐摄入量（RNI）来评价VA膳食摄入状况。结果：（1）共收集有效问卷302份，完成血清视黄醇检测的有302人，其中VA缺乏的检出率为14.90%，可疑VA缺乏为47.35%，未发现严重临床VA缺乏病例。（2）孕妇的年龄、药物补充是影响VA摄入的正相关因素（P<0.05），而孕前BMI、孕次、产次、文化程度则与VA摄入无关（P>0.05）。（3）孕妇的文化程度、药物补充是血清视黄醇浓度的影响因素，且血清视黄醇浓度与孕妇文化程度、药物补充呈现正相关（P<0.05）；而孕妇年龄、孕次、产次这3个因素与血清视黄醇浓度无关（P>0.05）。（4）血清中视黄醇浓度与膳食总VA摄入量正相关，膳食总VA摄入量越高，血清中视黄醇的浓度越高（r=0.137，P P<0.05）。结论：我院孕妇孕晚期的VA营养状况不容乐观，VA膳食摄入状况仍有待改善。孕妇年龄、文化程度、药物补充是影响膳食总VA水平和血清视黄醇水平的主要因素。 |
| 关键词: 孕晚期 维生素A 视黄醇 营养水平 |
| DOI：doi:10.13407/j.cnki.jpp.1672.108X.2019.12.003 |
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| 基金项目::国家自然科学基金青年基金,编号81401747。 |
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| Research about the Nutritional Level of Vitamin A among Pregnant Women in Late Pregnancy in the Second Affiliated Hospital of Chongqing Medical University |
| He Yuwei1, Zhou Jin1, Liu Huan2,Miao Jingkun2 |
| (1. The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China; 2. Children Hospital of Chongqing Medical University, Chongqing 400014, China) |
| Abstract: |
| Objective: To evaluate the nutritional status of VA in pregnant women in the second affiliated hospital of Chongqing Medical University, in order to provide reasonable suggestions for the nutritional status of pregnant women VA. Methods: A total of 332 pregnant women who underwent antenatal care in The Second Affiliated Hospital of Chongqing Medical University during the third trimester of September 2016-January 2017 were investigated. Using questionnaires and 24h dietary survey to understand the dietary composition of pregnant women. The level of retinol production in serum was determined by high performance liquid chromatography, and the daily intake of VA (RNI) was used to evaluate the dietary intake of VA. Results: (1) A total of 322 cases of pregnant women were collected. The detection rate of VA deficiency was 14.90%, the suspicious VA deficiency was 47.35%. There were no severe clinical VA deficiency cases. (2) The age and drug supplement of pregnant women were the positive correlation factors affecting the intake of VA (P=0.006, P=0.001), but the BMI before pregnancy, the birth order, the gravida para and education level were not related to the intake of VA (P>0.05). (3) At the same time, the educational level and drug supplement of pregnant women are the influencing factors of the serum retinol concentration, and the serum retinol concentration was positively correlated with pregnant women' educational level and drug supplement (P=0.001, P=0.000). However, the three factors of pregnant women’ age, the birth order and the gravida para were not related to the serum retinol concentration (P>0.05). (4) There was a positive correlation between the serum retinol concentration and total dietary VA intake. The higher the dietary total VA intake, the higher the serum retinol concentration (r=0.137, P=0.039). Conclusion: The nutritional status of VA in late pregnancy of pregnant women in our hospital was not optimistic, and the dietary intake of VA still needs to be improved. Age, education level and drug supplement of the pregnant women were the main factors affecting total dietary VA level and the serum retinol level. |
| Key words: Late pregnancy Vitamin A Retinol Nutritional level |
