| 摘要: |
| 目的：通过分析1例抽动症患儿使用氟哌啶醇导致神经阻滞剂恶性综合征的不良反应，为合理用药提供参考建议。方法：判断该神经阻滞剂恶性综合征和氟哌啶醇的相关性，并分析发生的原因和易感因素。结果：氟哌啶醇很可能是引起了该患儿神经阻滞剂恶性综合征的药物，经过药物的调整，病情已得到控制。结论：在使用氟哌啶醇中应密切监测症状体征，避免过快调整剂量，以免发生严重不良反应。 |
| 关键词: 氟哌啶醇 神经阻滞剂恶性综合征 抽动症 临床药师 |
| DOI：doi:10.13407/ j.cnki.jpp.1672.108X.2021.09.011 |
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| 基金项目: |
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| Adverse Drug Reactions of Suspected Neuroleptic Malignant Syndrome in a Child |
| Zhao Yiming, Shi Qiang, Liu Xiaohui, Wang Xiaoling |
| (Beijing Children’s Hospital, Capital Medical University, Beijing 100045, China) |
| Abstract: |
| Objective: To analyze the adverse drug reactions of neuroleptic malignant syndrome induced by haloperidol in one child with transient tic disorder, so as to provide reference for rational drug use. Methods: The correlation between neuroleptic malignant syndrome and haloperidol was determined, and the causes and susceptibility factors were analyzed. Results: Haloperidol was probably the drug that induced neuroleptic malignant syndrome in the child, and the condition was under control after medication modification. Conclusion: During the use of haloperidol, symptoms and signs should be closely monitored, and the dosage should be adjusted properly to avoid severe adverse drug reactions. |
| Key words: haloperidol neuroleptic malignant syndrome transient tic disorder clinical pharmacists |
