| 摘要: |
| [摘要]目的：探讨复方利多卡因乳膏在白血病和淋巴瘤患儿腰椎穿刺c中的应用效果。方法：选取2014-2016年我院行腰椎穿刺腰椎穿刺术鞘内注射药物的白血病和淋巴瘤患儿292例，按随机数表法分为试验组和对照组各146例。试验组在以腰椎穿刺点为圆心、半径为5 cm的局部皮肤涂抹0.5 mm厚复方利多卡因乳膏，采用医用3M贴膜覆盖2 h，去除贴膜和乳膏常规消毒后行腰椎穿刺术；对照组操作时采用利多卡因注射液局部麻醉后行腰椎穿刺术。采用改良面部表情评分法（FLACC）量表和Wong-Baker面部表情分级量表评价患儿疼痛程度，记录患儿穿刺前后心率、呼吸、血压、穿刺成功率、患儿穿刺后不适感及家属满意度。结果：试验组疼痛程度、穿刺后不适感低于对照组（P<0.05）。对照组穿刺后心率、呼吸、收缩压均明显较穿刺前加快（P<0.05），试验组穿刺后心率、呼吸、收缩压与穿刺前比较差异无统计学意义（P>0.05）。穿刺成功率两组比较差异无统计学意义，但试验组患儿家属满意度明显高于对照组。结论：复方利多卡因乳膏可明显减轻肿瘤患儿治疗过程中反复穿刺带来的疼痛，提高了患儿生活质量和医师工作效率，值得临床推广应用。 |
| 关键词: 复方利多卡因乳膏 儿童 白血病 淋巴瘤 腰椎穿刺术 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2021.10.005 |
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| 基金项目: |
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| Effects of Compound Lidocaine Cream on Lumbar Puncture in Children with Tumor |
| Gao Wenjuan, Cao Xiaoqin, Liu Hailing, Zhang Wenjun, Zhang Yuanyuan, Liu Zhigang |
| (The First Affiliated Hospital of Xi’an Jiaotong University, Shaanxi Xi’an 710061, China) |
| Abstract: |
| [Abstract] Objective: To probe into the effects of compound lidocaine cream on lumbar puncture in children with tumor. Methods: A total of 292 children with leukemia and lymphoma received intrathecal injection of lumbar puncture from 2014 to 2016 in our hospital were extracted to be divided into the experimental group and the control group via the random number table, with 146 cases in each group. In the experimental group, with the lumbar puncture point as the center, the local skin with the radius of 5 cm was smeared with 0.5 mm compound lidocaine cream, covered with the medical 3M film for 2 h, and the film and cream were removed and routinely disinfected before lumbar puncture. The control group received lumbar puncture after local anesthesia with lidocaine injection. Improved facial expression scoring (FLACC) scale and Wong-Baker facial expression scale were used to evaluate the pain degree of the children, and the heart rate, respiration, blood pressure, success rate of puncture, discomfort and family satisfaction were recorded before and after puncture. Results: The degree of pain and discomfort after puncture in the experimental group were lower than those in the control group (P<0.05). After puncture, the heart rate, respiration and systolic blood pressure in the control group were significantly faster than those before puncture (P<0.05), and the difference in heart rate, respiration and systolic blood pressure after puncture in the experimental group was not statistically significant (P>0.05). There was no significant difference in success rate of puncture between two groups, yet the satisfaction of the family members in the experimental group was significantly higher than that of the control group. Conclusion: Compound lidocaine cream can significantly reduce the pain caused by repeated puncture in the treatment of children with tumor, improve the quality of life of children and the efficiency of clinicians, and is worthy of clinical application. |
| Key words: compound lidocaine cream children leukemia lymphoma lumbar puncture |
