| 摘要: |
| [摘要]目的：评价临床药师开展药学服务对肾病综合征患儿合理用药的影响。方法：抽取我院肾病综合征住院患儿病历非干预组81份（2018年1-6月）及干预组83份（2018年7-12月），对比两组患儿用药依从性、不良反应发生率、治疗效果及对疾病认知方面差异。结果：干预组和非干预组用药依从性评分为（6.74±1.13）分和（3.25±1.56）分（P<0.05）；干预组在视物模糊、骨质疏松、糖尿病的不良反应发生率分别为3.61%、2.41%、0，均低于非干预组12.35%、9.87%、4.94%（P<0.05）；疾病认知方面干预组明显优于非干预组（P<0.05）。结论：通过临床药师系统全面的药学服务，能降低肾病综合征患儿药品不良反应的发生，提高用药的依从性及对疾病的认知程度。 |
| 关键词: 临床药师 肾病综合征 用药依从性 药学服务 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2021.04.012 |
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| 基金项目:全国医药经济信息网科技创新传播创新工程2017 年重点项目,编号CMEI2017KP00210。 |
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| Intervention of Pharmaceutical Care on Rational Drug Use in Children with Nephrotic Syndrome |
| Duan Yanyan, Ma Shuli, Pei Baofang, Chen Haiyan |
| (Children’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Henan Zhengzhou 450000, China) |
| Abstract: |
| [Abstract] Objective: To evaluate the effects of pharmaceutical care by clinical pharmacists on the rational drug use in children with nephrotic syndrome. Methods: Medical records of hospitalized children with nephrotic syndrome in our hospital were collected from 81 cases in the non-intervention group (from Jan. to Jun. 2018) and 83 cases in the intervention group (from Jul. to Dec. 2018). Differences in medication compliance, incidence of adverse drug reactions, treatment effects and disease cognition between two groups were compared. Results: The medication compliance scores of the intervention group and non-intervention group were respectively (6.74±1.13) points and (3.25±1.56) points (P<0.05). The incidences of adverse drug reactions in the intervention group such as blurred vision, osteoporosis and diabetes were respectively 3.61%, 2.41%, and 0, lower than 12.35%, 9.87%, and 4.94% in the non-intervention group (P<0.05). In terms of disease cognition, the intervention group was significantly better than the non-intervention group (P<0.05). Conclusion: Comprehensive pharmaceutical care by clinical pharmacists can reduce the incidence of adverse drug reactions in children with nephrotic syndrome, improve the medication compliance and the degree of cognition of the disease. |
| Key words: clinical pharmacists nephrotic syndrome medication compliance pharmaceutical care |
