| 摘要: |
| 目的：分析儿童新型冠状病毒（2019-nCoV）感染的临床特征，为临床诊治提供参考。方法：回顾性分析重庆大学附属三峡医院2020年2月1-11日收治的3例2019-nCoV感染患儿（男2例，女1例）的基本情况、流行病学资料、现病史、辅助检查，并描述其治疗经过及结局。结果：3例患儿年龄分别为7个月、2岁5个月、5岁2个月；感染途径均为家庭内传播；临床症状相对较轻，以呼吸道症状为主，其中1例无明显症状；实验室检查示白细胞、淋巴细胞水平均无明显降低，C反应蛋白（CRP）及降钙素原（PCT）水平均正常，胸部影像学改变较轻；经隔离治疗后均好转，无新增其他临床症状。结论：家庭内传播是儿童感染的主要途径，且儿童2019-nCoV感染临床症状相对成人较轻，甚至为无症状感染。 |
| 关键词: 新型冠状病毒 儿童 临床特征 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2020.06.006 |
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| 基金项目: |
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| Clinical Characteristics of Three Children with 2019 Novel Coronavirus Infection in Chongqing |
| Qiao Yingqin, Mo Yunbo, Peng Zhe, Yu Jie, Jiang Jianyu, Feng Yan, Xiao Hongzhou, Xiong Daoxue, Qin Xian, Chen Hongxia, Xu Junping |
| (Chongqing University Three Gorges Hospital, Chongqing Three Gorges Central Hospital, Chongqing 404000, China) |
| Abstract: |
| Objective: To analyze the clinical characteristics of children with 2019 novel coronavirus (2019-nCoV) infection, so as to provide reference for clinical diagnosis and treatment. Methods: Retrospective analysis was conducted on clinical data of three children (2 males, 1 female) with 2019-nCoV infection in Chongqing University Three Gorges Hospital from Feb. 1st to Feb. 11th, 2020. The basic information, epidemiological data, history of present illness and auxiliary examination were summarized, the treatment process and outcome were analyzed. Results: Three children were respectively 7 months, 2 years and 5 months, and 5 years and 2 months. The infection route was intra-family transmission. The clinical symptoms were relatively mild, respiratory symptoms were the main clinical manifestations, and one child was asymptomatic. There was no significant reduction in white blood cells and lymphocytes in laboratory examination, the levels of C-reactive protein (CRP) and procalcitonin (PCT) were within the normal range, and the chest radiographic changes were minor. The original clinical symptoms were improved after treatment in isolation, and no other clinical symptoms were observed. Conclusion: Intra-family transmission is the main infection route in children, and the clinical symptoms of children with 2019-nCoV infection are milder than those of adults, or even with asymptomatic infection. |
| Key words: 2019 novel coronavirus children clinical characteristics |
