| 摘要: |
| [摘要]目的：探讨儿童用药依从性及其影响因素。方法：回顾性分析2019年12月至2020年7月于我院就诊的1 573例患儿家属的问卷调查表，根据问卷调查结果将所选患儿分为用药困难组（n=142）和非用药困难组（n=1 431），统计儿童用药依从性情况，并采用Logistic回归分析儿童用药困难的危险因素。结果：1 573例患儿中, 用药完全依从235例（14.94%），基本依从1 027例（65.29%），极少依从169例（10.74%），用药困难142例（9.03%）。经多因素Logistic回归分析结果显示，年龄6个月~3岁、非独生子女、家属职业为体力劳动者或自由/全职、药品剂型为片剂、药品口味为中药味、未按医师交代给药频次给药、未按医师交代给药剂量给药、因药品出现不良反应而停药、干预措施为心理安慰或无干预措施是儿童用药困难的独立危险因素（OR分别为2.659、2.691、1.784、1.939、2.425、2.201、2.635、2.218、2.010、1.576、1.669，P均<0.05）。结论：儿童用药困难发生率较高，而影响儿童用药困难的危险因素与患儿年龄、是否为独生子女、家属职业、药品剂型、药品口味、是否按医师交代给药频次给药、是否按医师交代给药剂量给药、是否因药品出现不良反应而停药以及干预措施等有关，临床应当予以重视并予以相关措施以提高儿童用药依从性。 |
| 关键词: 儿童 用药依从性 用药困难 问卷调查 危险因素 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2022.01.009 |
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| 基金项目:国家卫生健康委医管中心研究项目,医管中心药械处[2019]053 号;中国医药新闻信息协会儿童安全用药分会课题,编号20190001。 |
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| Children’s Medication Compliance and Its Influencing Factors |
| Niu Zhenxi, Xing Yabing, Ma Shuli |
| (Children’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Henan Zhengzhou 450018, China) |
| Abstract: |
| [Abstract] Objective: To probe into the children’s medication compliance and its influencing factors. Methods: Questionnaire survey was performed on 1,573 children’s family members admitted into our hospital from Dec. 2019 to Jul. 2020. According to the questionnaire results, the enrolled children were divided into the medication difficulty group (n=142) and non-medication difficulty group (n=1,431). The medication compliance of children was analyzed, and the risk factors of medication difficulty of children were analyzed by Logistic regression. Results: Of the 1,573 cases, 235 cases (14.94%) were completely complied, 1,027 cases (65.29%) were basically complied, 169 cases (10.74%) were rarely complied, and 142 cases (9.03%) had difficulty with medication compliance. The results of multivariate Logistic regression analysis showed that children from 6 months to 3 years, non-only child, family members with occupation of manual laborers or free/full-time, dosage form of tablets, taste of traditional Chinese medicine, irrational administration without clinicians’ instructions for frequency of administration, irrational dosage without without clinicians’ instructions for dosage of administration, drug withdraw for adverse drug reactions, with intervention measures of psychological comfort or no intervention measures were independent risk factors for children’s medication difficulty (OR=2.659, 2.691, 1.784, 1.939, 2.425, 2.201, 2.635, 2.218, 2.010, 1.576, 1.669, P<0.05). Conclusion: The incidence of medication difficulty in children is relatively high, and the risk factors that affect children’s medication compliance are related to the age of children, non-only child, occupation of family members, dosage form, taste, administration with clinicians’ instructions for frequency of administration, dosage with clinicians’ instructions for dosage of administration, and drug withdraw for adverse drug reactions. Clinical attention should be paid and relevant measures should be taken to improve children’s medication compliance. |
| Key words: children medication compliance medication difficulty questionnaire survey risk factors |
