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临床药师参与1 例肝母细胞瘤患儿的治疗实践及文献复习
程艺,周艳,樊鑫,吴青
0
((重庆医科大学附属儿童医院,儿童发育疾病研究教育部重点实验室,国家儿童健康与疾病临床医 学研究中心,儿童发育重大疾病国家国际科技合作基地,儿科学重庆市重点实验室,重庆 400014))
摘要:
目的:建立应对肿瘤患儿发热的临床思维以及化疗并发恶心、呕吐等胃肠道不良反应的治疗方案。方法:临床药师参与 1 例肝母细胞瘤化疗患儿的治疗过程,全面分析患儿发热原因,与临床医师讨论并优化治疗方案。查询国内外最新研究进展, 及时调整止吐药物剂量。结果:临床医师采纳临床药师建议,经个体化调整止吐药物剂量后患儿呕吐得到控制,最终经外科处 理后患儿体温恢复正常。结论:临床药师参与临床治疗,全面分析患儿发热原因并查找化疗相关突破性恶心、呕吐的治疗进展, 协助医师调整用药,有利于发挥药师在治疗团队中的作用。
关键词:  临床药师  发热  化疗相关性恶心呕吐  药学监护
DOI:doi:10.13407/j.cnki.jpp.1672-108X.2023.04.005
基金项目:
Clinical Pharmacist’s Participated in the Treatment of a Child with Hepatoblastoma and Literature Review
Cheng Yi, Zhou Yan, Fan Xin, Wu Qing
((Children’s Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health, China International Science and Technology Base of Child Development and Critical Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China))
Abstract:
Objective: To establish clinical thinking to deal with fever in children with tumors, as well as the treatment plan for gastrointestinal adverse reactions such as nausea and vomiting caused by chemotherapy. Methods: Clinical pharmacist’s participated in the whole treatment process of the child, comprehensively analyzed the causes of fever in the child. And the pharmacists actively inquired the latest research progress at home and abroad, and adjusted the dose of antiemetic drugs. Results: The clinician adopted the advice of the clinical pharmacist and controlled the vomiting of the child after increasing the dose of antiemetic drugs. Finally, the temperature of the child returned to normal after surgical treatment. Conclusion: Clinical pharmacists participate in clinical treatment, comprehensively analyze the causes of fever in children, search for the treatment progress of breakthrough of nausea and vomiting during chemotherapy, and assist physicians in adjusting medication, which is conducive to giving full play to the role of pharmacists in the treatment team.
Key words:  clinical pharmacist  fever  chemotherapy associated nausea and vomiting  pharmaceutical care

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