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临床药师参与 1 例鼠伤寒沙门菌肠炎患儿抗感染治疗的药学实践
宋文琳1,2,赵凯2,段露芳2
0
(1. 苏州市吴江区儿童医院,江苏苏州 215200;2. 苏州市立医院,江苏苏州 215002)
摘要:
目的:对临床药师参与的 1 例鼠伤寒沙门菌肠炎患儿的抗感染治疗进行分析,为提高患儿的用药安全提供参考。 方法:临床药师通过查阅文献得知鼠伤寒沙门菌感染性腹泻治愈后,通过粪便的排菌周期较长,建议临床医师及时停用抗菌药物,避免恢复期长期使用抗菌药物延长患儿的排菌周期,增加药物不良反应,甚至引发二重感染。 结果:临床医师采纳药师建议,停用抗菌药物,住院期间未观察到明显药物不良反应。 结论:临床药师应关注鼠伤寒沙门菌肠炎患儿的抗感染治疗疗程,提高患儿用药安全性。
关键词:  临床药师  鼠伤寒沙门菌  抗感染  恢复期  排菌时间
DOI:10. 13407/ j. cnki. jpp. 1672-108X. 2023. 07. 002
基金项目:2021年苏州市科技发展计划,编号SKJYD2021171
Pharmaceutical Practice of Anti-Infective Treatment for a Child with Salmonella Typhimurium Enteritis by Clinical Pharmacists
Song Wenlin1,2, Zhao Kai2, Duan Lufen2
(1. Children’s Hospital of Suzhou Wujiang District, Jiangsu Suzhou 215200, China;2. Suzhou Municipal Hospital, Jiangsu Suzhou 215002, China)
Abstract:
Objective: To analyze the anti-infective treatment for a child with Salmonella typhimurium enteritis participated by clinical pharmacists, so as to provide reference for improving the medication safety. Methods: Through literature review, the clinical pharmacists suggested that S. typhimurium infected diarrhea had a long elimination cycle through the feces after it was cured. It was recommended that clinicians stop using antibiotics in a timely manner to avoid the long-term use of antibiotics during the recovery period to prolong the elimination cycle of children, which increased adverse drug reactions and even caused secondary infection. Results: The clinicians adopted pharmacists’ suggestions and stopped antibiotics administration, and no obvious adverse drug reactions were observed during hospitalization. Conclusion: Pharmacists should focus on the treatment course of anti-infective treatment for children with S. typhimurium enteritis to improve the medication safety.
Key words:  clinical pharmacists  Salmonella typhimurium  anti-infective  recovery period  duration of excretion

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