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利多卡因气雾剂与利多卡因注射液分别复合双氯芬酸钾栓对儿童包皮环切手术患者的镇痛效果比较
徐珂1,殷秋红1,穆亚宁1,成龙2
0
(1.宝鸡市妇幼保健院,陕西宝鸡 721000;2. 遵义医科大学药学院,贵州遵义 563006)
摘要:
目的:比较利多卡因气雾剂联合双氯芬酸钾栓与利多卡因注射液联合双氯芬酸钾栓对儿童包皮环切手术的镇痛效果。方法:采用随机数表法将宝鸡市妇幼保健院 260 例拟行包皮环切术的患儿分为对照组和研究组各 130 例,对照组给予利多卡因局部阴茎根部阻滞联合双氯芬酸钾栓进行局麻镇痛处理,研究组应用利多卡因气雾剂表面喷雾联合双氯芬酸钾栓进行局部麻醉镇痛处理,比较两组患儿的镇痛效果。 结果:与对照组比较,研究组患儿术前配合度较高,且手术操作时间、麻醉起效时间均较短(P<0. 05)。 研究组患儿手术开始时(T0)、切下包皮时(T1)、手术结束时(T2)疼痛程度 FLACC 评分均低于对照组(P 均<0. 05)。 研究组患儿麻醉总满意率高于对照组(P<0. 05)。 结论:利多卡因气雾剂联合双氯芬酸钾栓对儿童包皮环切手术镇痛效果较优,术后并发症发生率较低,患儿麻醉总体满意度好,值得临床推广应用。
关键词:  利多卡因气雾剂  利多卡因注射液  双氯芬酸钾栓  包皮环切  镇痛
DOI:10.13407/j.cnki.jpp.1672-108X.2023.08.013
基金项目:
Comparison of Analgesic Effects of Lidocaine Aerosol and Lidocaine Injection Combined with Diclofenac Potassium Suppository in Children Undergoing Circumcision
Xu Ke1, Ying Qiuhong1, Mu Yaning1, Cheng Long2
(1. Baoji Maternal and Child Health Care Center, Shaanxi Baoji721000, China; 2. School of Pharmacy, Zunyi Medical University, Guizhou Zunyi 563006, China)
Abstract:
Objective: To compare the analgesic effects of lidocaine aerosol and lidocaine injection combined with diclofenac potassium suppository in children undergoing circumcision. Methods: A total of 260 children undergoing circumcision in Baoji Maternal and Child Health Care Center were divided into the study group and control group via the random table method, with 130 cases in each group. The control group was given lidocaine local injection anesthesia with diclofenac potassium suppository, while the study group received lidocaine aerosol with diclofenac potassium suppository. The anesthetic effects of two groups were compared. Results: Compared with the control group, the preoperative coordination of the study group was higher, and the operation time and onset time of anesthesia were shorter (P<0. 05). The FLACC scores of pain degree at the beginning of surgery (T0), after circumcision (T1) and at the end of surgery (T2) in the study group were lower than those in the control group (P<0. 05). The total satisfaction rate of anesthesia in the study group was higher than that of the control group (P<0. 05). Conclusion: Lidocaine aerosol combined with diclofenac potassium suppository has better analgesic effect on circumcision, with lower postoperative complication rate and higher overall satisfaction rate, which is worthy of clinical promotion and application.
Key words:  lidocaine aerosol  lidocaine injection  diclfenac potassium suppository  circumcision  analgesia

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