| 摘要: |
| 目的:分析某儿童医院含毒性饮片中成药临床应用情况,评估该类制剂的安全性和有效性。方法:对该院2021 年3 月
31 日门急诊中成药处方进行横断面调查。结果:口服类含毒性饮片中成药诊断与用药相符率为98. 2%;1 例用药记录无临床诊
断,1 例联合用药不适宜;单次剂量及用药频次同时正确率为24. 6%;外用类含毒性饮片中成药诊断与用药相符率为96. 4%;
1 例联合用药无诊断,4 例联合用药不适宜,3 例日用量偏大,2 例选择药物不适宜。结论:该院含毒性饮片中成药诊断与用药相
符率>95%,口服类含毒性饮片中成药使用较为保守,日总量偏小,可能导致药品有效性降低;外用类含毒性饮片中成药有超药
品说明书使用现象,日总量偏大;联合用药较为普遍,也有两种含毒性饮片中成药联用现象,应加强管理。 |
| 关键词: 含毒性饮片中成药 安全性 有效性 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2024.04.005 |
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| 基金项目: |
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| Clinical Application of Chinese Patent Medicine Containing Toxic Decoction Pieces in a Children’s Hospital |
| Li Xingui, Chen Guanru, Chen Huiying, Wang Zhuoyun |
| ((Anhui Children’s Hospital, Hefei 230051, China)) |
| Abstract: |
| Objective: To analyze the clinical application of Chinese patent medicine containing toxic decoction pieces in a children’s
hospital, and to evaluate the safety and efficacy of such preparations. Methods: A cross-sectional survey was performed on prescription
of Chinese patent medicine in the emergency department of the hospital on Mar. 31st , 2021. Results: The consistency rate between
diagnosis and medication of oral Chinese patent medicine containing toxic decoction pieces was 98. 2%. One case had no clinical
diagnosis in the medication record, and 1 case was unsuitable for drug combination. The accuracy rate of single dose and frequency of
medication was 24. 6%. The consistency rate between diagnosis and medication of topical Chinese patent medicine containing toxic
decoction pieces was 96. 4%. One case was not diagnosed with drug combination, 4 cases were inappropriate for drug combination,
3 cases had a large daily dosage, and 2 cases were not suitable for drug selection. Conclusion: The consistency rate between diagnosis
and medication of Chinese patent medicine containing toxic decoction pieces in the hospital is >95%. The use of oral Chinese patent
medicine containing toxic decoction pieces is relatively conservative, and the daily total dose amount is small, which may lead to a
decrease in the effectiveness of drugs. The use of topical Chinese patent medicine containing toxic decoction pieces has the phenomenon
of off-label drug use, the daily total dose amount is large. Drug combination is more common, and there are also application with two
kinds of Chinese patent medicine containing toxic decoction pieces, which should be strengthened. |
| Key words: toxic tablets of proprietary medicine safety efficacy |
