| 摘要: |
| 目的:总结并分享医师和药师联合治疗1 例婴儿肺部烟曲霉菌感染的经验。方法:临床药师参与1 例婴儿肺部烟曲霉菌
感染的治疗过程,从药物选择、血药浓度监测及不良反应等方面优化给药方案,开展药学监护,实施个体化给药。结果:患儿通
过药学监护服务及时避免了不良事件并取得了良好的感染控制效果,病情好转出院。结论:治疗药物监测( TDM) 是儿童使用
药物后药效评估和不良反应监护的重要手段,临床药师利用专业优势参与制定个体化给药方案,可促进临床合理用药。 |
| 关键词: 伏立康唑 烟曲霉 治疗药物监测 婴儿 药学监护 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2024.10.004 |
|
| 基金项目:国家自然科学基金,编号82003829;广州市科技计划项目,编号202102021103。 |
|
| Pharmaceutical Care for an Infant with Pulmonary Infection of Aspergillus Fumigatus Through TherapeuticDrug Monitoring |
| Liang Qianying, Mo Xiaolan, Wu Weizhe, Wu Yanlan, Zhang Jianhui |
| ((Guangzhou Women and Children’s Medical Center,
Guangzhou Medical University, Guangzhou 515510, China)) |
| Abstract: |
| Objective: To summarize and share the experience of clinicians and pharmacists in the treatment of an infant with pulmonary
infection of Aspergillus fumigatus. Methods: Clinical pharmacists participated into the treatment of an infant with pulmonary infection of
A. fumigatus. The drug administration regimen was optimized from the aspects of drug selection, blood concentration monitoring and
adverse drug reactions, and pharmaceutical care was carried out to implement individualized drug administration. Results: The
pharmaceutical care in the therapeutic course of the child avoid worsening of adverse drug reactions and achieved the goal in controlling
pulmonary infection of A. fumigatus. The infant was discharged from the hospital with improved conditions. Conclusion: Therapeutic
drug monitoring (TDM) is an important means of assessing drug efficacy and monitoring adverse drug reactions in children. Clinical
pharmacists take advantage of the professional strength to participate into the formulation of individualized drug administration regimen,
which can promote clinical rational drug use. |
| Key words: voriconazole Aspergillus fumigatus therapeutic drug monitoring infant pharmaceutical care |
