| 摘要: |
| 目的:以病例为基础探讨婴幼儿湿疹与使用维生素AD 滴剂的相关性。方法:基于诺氏评估量表分析5 例使用维生素
AD 滴剂出现婴幼儿湿疹的病例,评价患儿出现湿疹与使用维生素AD 滴剂的相关性。结果:5 例患者诺氏评分为5~8 分,即湿
疹与维生素AD 滴剂“很可能相关”是滴剂辅料中含有的花生油成分是可能的诱因。结论:临床诊治时,诺氏评估量表的分数可
为临床药师排除或判断患儿出现湿疹与所用维生素AD 滴剂的关联性。诺氏评分高于4 分时,提示不仅要选择活性成分,还要
从整体上选择药物配方,以减轻患者的不良反应。 |
| 关键词: 维生素AD 滴剂 湿疹 花生油 过敏 药品不良反应 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2025.08.012 |
|
| 基金项目:基金项目:广东省药品监督管理局2022 年科技创新项目,编号2022YDB24;东莞市社会发展科技项目,编号20211800901922。 |
|
| Correlation Analysis of Vitamin AD Drops and Infantile Eczema Based on Naranjo’s Assessment Scale |
| Luo Wei, Lan Mingxiong, Ma Aiwen, Xiao Ziting, Tian Guoliang |
| (Dongguan Institute for Food and Drug Control,
Guangdong Dongguan 523781, China) |
| Abstract: |
| Objective: To explore the correlation between infantile eczema and vitamin AD drops based on cases. Methods: Based on
the Naranjo’s Assessment Scale, five cases of infantile eczema induced by vitamin AD drops were analyzed to evaluate the correlation
between the occurrence of eczema and vitamin AD drops. Results: The Naranjo’s Assessment Scale score of five patients were from 5 to
8 points, indicated that eczema were “possibly related” to the use of vitamin AD drops, for the peanut oil in the excipients may be an
inducer of eczema. Conclusion: In clinical diagnosis and treatment, the Naranjo’s Assessment Scale score can help clinical pharmacists
rule out or determine the correlation between infantile eczema and vitamin AD drops. When the score is higher than 4 points, it is
suggested that not only the active component but the overall drug formulation should be selected to help alleviate the adverse drug
reactions. |
| Key words: vitamin AD drops eczema peanut oil allergy adverse drug reactions |
