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| 基于芩香清解口服液循证对儿童流感治疗中辛凉解表类制剂的临床综合评价示范研究 |
| 马新玲1,郭春彦2,梁菁1,王洋洋1,尉耘翠2,曹旺2,孙燕燕1,王晓玲2 |
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| (1. 天津市儿童医院,天津大学儿童医院,天津 300134; 2. 首都医科大学附属北京儿童医院,北京 100045) |
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| 摘要: |
| 目的:评估以芩香清解口服液为例的辛凉解表类口服制剂在治疗儿童流感中的临床价值,为儿科合理用药提供参考。
方法:基于文献检索和数据调研,对芩香清解口服液的有效性、安全性、适宜性、可及性、创新性、经济性及中医药特色进行临床
综合评价。结果:芩香清解口服液在治疗儿童流感中展现出与磷酸奥司他韦相当的临床疗效,不良反应发生率较低。该中药制
剂具有多项国家发明专利和鲜明的中医药特色,为儿童专用药,在医疗机构配备率仍有待提高。结论:芩香清解口服液治疗儿
童流感疗效确切,安全可靠,综合评价认为具有较高的临床价值;本研究为其临床合理使用提供了循证依据。 |
| 关键词: 芩香清解口服液 儿童 流感 药品临床综合评价 抗病毒药物 |
| DOI：10.13407/j.cnki.jpp.1672-108X.2025.06.001 |
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| 基金项目:“十三五”重大新药创制科技重大专项,编号2018ZX09721-003。 |
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| Comprehensive Clinical Evaluation of Xinliang Jiebiao Formulations in the Treatment of Influenza in Children Based on Evidence from Qinxiang Qingjie Oral Liquid |
| Ma Xinling1, Guo Chunyan2, Liang Jing1, Wang Yangyang1, Yu Yuncui2, Cao Wang2, Sun Yanyan1, Wang Xiaoling2 |
| (1. Tianjin Children’s Hospital, Children’s Hospital, Tianjin University, Tianjin 300134, China; 2. Beijing Children’s Hospital, Capital Medical University, Beijing 100045, China) |
| Abstract: |
| Objective: To evaluate the clinical value of Xinliang Jiebiao oral preparations (Qinxiang Qingjie oral liquid) in the
treatment of influenza in children, and to provide reference for rational drug use in children. Methods: Based on literature retrieval and
data investigation, comprehensive clinical evaluation was conducted on the effectiveness, safety, suitability, accessibility, innovation,
economy and traditional Chinese medicine characteristics of Qinxiang Qingjie oral liquid. Results: Qinxiang Qingjie oral liquid in the
treatment of influenza in children showed comparable clinical efficacy as oseltamivir phosphate, with lower incidence of adverse drug
reactions. As a patented pediatric-specific traditional Chinese medicine agent, its clinical availability needs expansion. Conclusion:
Qinxiang Qingjie oral liquid has a definite therapeutic effect on influenza in children, which is safe and reliable. The comprehensive
evaluation suggests that it has a high clinical value. This study provides guidelines and evidence-based basis for the rational clinical use. |
| Key words: Qinxiang Qingjie oral liquid children influenza comprehensive clinical drug evaluation antiviral agents |
