| 摘要: |
| 目的:了解安徽省儿童医院肾脏病门诊超说明书用药现状及运用循证评价超说明书用药合理性,并分析对策。方法:通
过我院药学管理系统抽取2024 年肾脏病门诊处方,筛选出超说明书用药处方,对超说明书用药合理性进行分析。结果:共纳入
4 842 张处方,其中超说明书用药共1 800 张(37. 17%),超说明书用药合理处方共1 708 张(94. 89%)。不合理处方共92 张
(5. 11%)。结论:我院肾脏病门诊超说明书用药现象普遍,临床医师用药应权衡利弊,遵守国家相关政策规定,合理用药,保障
儿童用药安全。 |
| 关键词: 儿童 肾脏病 超说明书 循证评价 合理用药 |
| DOI：10.13407/j.cnki.jpp.1672-108X.2025.12.012 |
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| 基金项目: |
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| Analysis and Evidence-Based Evaluation of Off-Label Drug Use in Nephrology Outpatient Department ofAnhui Children’s Hospital |
| Chen Huiying1, Dai Xuesong2, Chen Guanru1, Ruan Wenyi1, Cai Heping1 |
| (1. Anhui Children’ s Hospital, Hefei
230000, China; 2. Anhui Medical University, Hefei 230000, China) |
| Abstract: |
| Objective: To investigate the current status of off-label drug use in the Nephrology Outpatient Department of Anhui
Children’s Hospital, evaluate the rationality of off-label drug use through evidence-based evaluation, and analyze the countermeasures.
Methods: Annual Nephrology Outpatient prescriptions in 2024 were extracted through the pharmacy management system, and off-label
drug use prescriptions were screened out. The rationality of off-label drug use was analyzed. Results: A total of 4,842 prescriptions were
enrolled, among which 1,800 prescriptions (37. 17%) were off-label, and 1,708 prescriptions were rational off-label drug use
(94. 89%). There were 92 irrational prescriptions (5. 11%). Conclusion: Off-label drug use is common in the Nephrology Outpatient
Department of our hospital. Clinicians should consider the advantages and disadvantages, comply with the relevant national policies and
regulations, and use drugs rationally to ensure the medication safety in children. |
| Key words: children kidney disease off-label drug use evidence-based evaluation rational drug use |
