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| 基于中医思维的儿童中成药专项处方点评体系构建与应用: 以病毒合剂为例 |
| 高艳1,2,魏悦1,2,熊永毫1,2,陶然1,2,孙燕燕1,2,杜文娟1,2 |
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| ([1. 天津市儿童医院(天津大学儿童医院),天津 300134;2. 天津市儿童出生缺陷防治重点实验室,天津 300134]) |
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| 摘要: |
| 目的:构建基于中医思维的中成药处方点评体系,以病毒合剂为例,探索其在儿童合理用药中的应用价值,提升处方规范性、适宜性与临床用药安全。方法:采用按月分层抽样法,从天津市儿童医院医院信息系统(HIS)中抽取2024 年7 月至2025 年6 月含病毒合剂的中成药处方3 600 张,依据《中成药临床应用指导原则》等规范,结合中医辨证理论与药物组方特点,制定涵盖规范性、适宜性(适应证、用法用量、重复用药、联合用药)及超常处方的多维点评规则,进行系统评价与问题分析。结果:共检出不合格处方121 张,处方合格率为96. 64%。不合格处方中,不规范处方48 张(39. 67%),主要问题为开具时限不规范(45 张,37. 19%);不适宜处方73 张(60. 33%),以用法用量不适宜为主(50 张,41. 32%);未发现超常处方。结论:基于中医理论的处方点评体系能有效识别中成药使用中的关键问题,尤其适用于儿童用药的合理性评估。该模式有助于促进中成药处方的规范化与个体化,为临床合理用药提供理论支持与实践路径。 |
| 关键词: 中医思维 处方点评 病毒合剂 儿童用药 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2026.04.004 |
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| 基金项目:妇幼健康领域全国名老中医药专家传承工作室建设项目;天津市医学重点学科建设资助项目,编号TJYXZDXK-3-016B。 |
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| Construction and Application of the Special Prescription Review System for Chinese Patent Medicines in Children Based on Traditional Chinese Medicine Thinking: a Case Study of Bingdu Mixture |
| Gao Yan1,2, Wei Yue1,2, Xiong Yonghao1,2, Tao Ran1,2, Sun Yanyan1,2, Du Wenjuan1,2 |
| (1. Tianjin Children’s Hospital(Children’ s Hospital, Tianjin University), Tianjin 300134, China; 2. Tianjin Key Laboratory of Birth Defects for Prevention andTreatment, Tianjin 300134, China)) |
| Abstract: |
| Objective: To construct the prescription review system of Chinese patent medicines based on traditional Chinese medicine thinking, and to explore the rational application value of Bingdu mixture in children, so as to improve the standardization, suitability and clinical drug safety of prescriptions. Methods: A total of 3,600 traditional Chinese medicine prescriptions containing Bingdu mixture were extracted by using a stratified monthly sampling method from the hospital information system (HIS) of Tianjin Children’s Hospital from Jul. 2024 to Jun. 2025. According to the Guidelines for Clinical Application of Chinese Patent Medicines and other norms, combined with the theory of traditional Chinese medicine syndrome differentiation and characteristics of drug formulation, the multidimensional review rules covering standardization, suitability (indication, dosage and usage, repeated medication, drug combination) and abnormal prescriptions were formulated, and systematic review and problem analysis were carried out. Results: A total of 121 unqualified prescriptions were detected, with a qualification rate of 96. 64%. There were 48 non-standard prescriptions (39. 67%), with the main problem of non-standard prescribing duration (45 prescriptions, 37. 19%). Seventy-three were inappropriate prescriptions (60. 33%), with inappropriate dosage and usage being the most common issue ( 50 prescriptions, 41. 32%). No exceptionalprescriptions were detected. Conclusion: The prescription review system based on traditional Chinese medicine theory can effectively identify key issues in the use of Chinese patent medicines, demonstrating particular applicability for assessing rational drug use in children. This model contributes to promoting the standardization and individualization of Chinese patent medicine prescriptions, offering theoretical support and a practical pathway for enhancing clinical rational drug use. |
| Key words: traditional Chinese medicine thinking prescription review Bingdu mixture pediatric medication |
