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川崎病罕见并发胆汁淤积性肝炎、毛细血管渗漏综合征及右心室增 大1 例并文献复习
郑雪艳,陈艾,周元琳,李磊,沈晓佳
0
(四川大学华西临床医学院,四川大学附属成都市第二人民医院,成都市第二人民医 院,成都 610011)
摘要:
目的:提高临床对儿童川崎病罕见并发症的认识。方法:回顾性分析1 例我院收治的川崎病合并胆汁淤积性肝炎、毛细 血管渗漏综合征及右心室增大患儿的临床资料,并进行文献复习。结果:1 例4 岁9 个月男童,因“发热伴颈部疼痛4 天,黄疸半 天”入院,诊断为川崎病、胆汁淤积性肝炎、毛细血管渗漏综合征、右心室增大,给予静脉注射免疫球蛋白、甲泼尼龙、阿司匹林、 白蛋白及对症治疗。患儿预后良好,未见心脏后遗症。结论:川崎病并发胆汁淤积性肝炎、毛细血管渗漏综合征及右心室增大 较罕见,对于表现为非典型症状的持续发热患儿,应保持对川崎病的高度警惕,避免延误最佳治疗时机。
关键词:  川崎病  胆汁淤积性肝炎  毛细血管渗漏综合征  右心室增大  儿童
DOI:doi:10.13407/j.cnki.jpp.1672-108X.2026.02.011
基金项目:基金项目:成都市卫健委基金资助项目,编号2024606。
Kawasaki Disease Complicated with Cholestatic Hepatitis, Capillary Leak Syndrome and Right Cardiomegaly: aCase Report and Literature Review
Zheng Xueyan, Chen Ai, Zhou Yuanlin, Li Lei, Shen Xiaojia
(West China School of Medicine, Sichuan University, Sichuan University Affiliated Chengdu Second People’s Hospital, Chengdu Second People’s Hospital, Chengdu 610011, China)
Abstract:
Objective: To improve the clinical understanding of rare complication of Kawasaki disease in children. Methods: Retrospective analysis was performed on clinical data of a child diagnosed with Kawasaki disease complicated with cholestatic hepatitis, capillary leak syndrome, and right cardiomegaly in our hospital, and literature review was conducted. Results: A 4 years and 9-month-old boy was admitted into our hospital with chief complaints of “fever accompanied by neck pain for 4 days, and jaundice for half a day”. The child was diagnosed with Kawasaki disease, cholestatic hepatitis, capillary leak syndrome, and right cardiomegaly. After administration of intravenous immunoglobulin, methylprednisolone, aspirin, albumin and symptomatic treatment, the prognosis was good and no cardiac sequelae were observed. Conclusion: The concurrent occurrence of cholestatic hepatitis, capillary leak syndrome and right cardiomegaly is rare. A high index of suspicion of Kawasaki disease should be maintained in patients presenting with persistent fever and atypical symptoms to avoid delaying the optimal treatment.
Key words:  Kawasaki disease  cholecystitis hepatitis  capillary leak syndrome  right cardiomegaly  children

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