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铜绿假单胞菌(Pseudomonas areuginas,PA)属于条件致病菌,最常引起呼吸道感染,其次有泌尿系统、皮肤、软组织感染,还可引起菌血症等。PA的显著特点是可分泌绿脓菌素,它是需氧的、引起医院化脓性感染的主要病原体之一,属于革兰阴性杆菌,普遍存在于大自然中。PA感染病死率有逐年升高趋势,有报道1996-2010年PA感染菌血症的患者的病死率由16%升至26%。目前PA对常用抗菌药物耐药率逐渐升高,故选择有效抗菌药物抗PA感染对改善患者预后、降低病死率至关重要。 |
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DOI:doi:10.13407/j.cnki.jpp.1672-108X.2018.01.019 |
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Antimicrobial Agents in the Treatment of Pseudomonas Aeruginosa |
Jin Shujuan, Liu Quanbo |
(Children's Hospital of Chongqing Medical University, Training Base of Clinical Resident Standard Training in Chongqing, Ministry of Education Key Laboratory of Child Development and Disorders, Key Laboratory of Pediatrics in Chongqing, China International Science and Technology Cooperation Base for Child Development and Critical Disorders, Chongqing 400014, China) |
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