| 摘要: |
| [摘要]乙型肝炎病毒(HBV)感染正严重威胁人类健康,目前全球超过3.4亿人感染HBV,我国作为HBV感染的流行地区,超过10%的人是HBV慢性携带者,其中
25%-40%的患者会进展成为肝硬化或肝癌,约1/3最终死于HBV相关疾病。HBV表面可形成多种外膜蛋白,preS1蛋白是其组成成分之一,位于HBV颗粒表面,其上有结合肝细胞膜的主要位点,具有极强的免疫原性,在HBV颗粒的组装和成熟中具有重要作用。 |
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| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2018.02.017 |
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| 基金项目: |
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| Research on preS1 Protein of HBV |
| He Meilin, Xu Hongmei |
| (Children's Hospital of Chongqing Medical University, Training Base of Clinical Resident Standard Training in Chongqing, Ministry of Education Key Laboratory of Child Development and Disorders, Key Laboratory of Pediatrics in Chongqing,Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing 400014, China)) |
| Abstract: |
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