| 摘要: |
| 目的:分析我院儿科急诊超说明书用药情况,为规范儿科合理用药提供数据支持。方法:随机抽取我院2014年9月至2015年9月儿科急诊处方6 720张,根据药品说明书判断是否超说明书用药,并分析超说明书用药的类型、不同年龄段超说明书用药发生率及药品种类等。结果:6 720张处方,共19 587条用药医嘱。其中超说明书用药处方4 307张,占总处方的64.09%;超说明书用药医嘱5 937条,占总医嘱条数的30.31%。前3位超说明书用药类型分别是无儿童用药信息(43.47%)、超适应证用药(35.25%)、超给药频次(15.10%)。结论:我院儿科急诊超说明书用药较为普遍,医疗过程中存在很大的风险。药品说明书中儿科用药信息严重缺乏,需要促进和规范儿童药物临床试验,为儿童用药提供更多的证据。 |
| 关键词: 儿科 急诊 儿童用药 超说明书用药 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2017.01.013 |
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| 基金项目: |
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| Analysis of Off-Label Drug Use in Our Pediatric Emergency Outpatients |
| Liu Xin, Zhang Sixi, Li Qinyuan, Xu Jingbo |
| (The First Hospital of Jilin University, Jilin Changchun 130021, China) |
| Abstract: |
| Objective: To analyze the situation of off-label drug use in our pediatric emergency outpatients, provide data support for the specification of pediatrics rational drug use. Methods: Selected 6,720 of pediatric emergency prescriptions randomly from September 2014 to September 2015, according to drug instructions content to determine off-label drug use, and analyzed the type of off-labels and incidence of different ages, drug variety and so on. Results: A total of 6,720 prescriptions with 19,587 medication
orders were selected. Among them, the off-label prescriptions were 4,307, 64.09% of total prescriptions. Off-label medication orders were 5,937, 30.31% of the total number of medical advice. The top three off-label medication instructions were no pediatric information (43.47% ), super indications (35.25% ), administration of super frequency (15.10% ). Conclusion: Off-label drug use in our pediatric emergency outpatients is common, a great risk exist in medical procedures. Drug information is serious insufficient about children. It's need to promote and standardize clinical trials of medicines for children, and provide more evidence for children medication. |
| Key words: pediatrics emergency drug use for pediatrics off-label drug use |
