| 摘要: |
| 目的：建立复B阿托品溶液的含量测定方法。方法：采用高效液相色谱（HPLC）法分别对处方中维生素B1、维生素B2、维生素B6、烟酰胺及硫酸阿托品进行定量分析。结果：维生素B1、维生素B2、维生素B6、烟酰胺及硫酸阿托品分别在其最大吸收波长下达到基线分离，线性范围较宽且线性关系良好。结论：所建立的方法简便可行，重现性好，可用于复Ｂ阿托品溶液的质量控制。 |
| 关键词: 复B阿托品溶液 高效液相色谱法 含量测定 |
| DOI：10.13407/j.cnki.jpp.1672-108X.2017.07.017 |
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| 基金项目: |
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| Content Determination of Various Components in Vitamin B Complex Atropine Solution |
| Han Lin, Wang Qingyang, Shi Qinyi |
| (Xuzhou Children’s Hospital of Jiangsu Province, Jiangsu Xuzhou 221006, China) |
| Abstract: |
| Objective: To establish a method for determination of Vitamin B Complex Atropine Solution. Methods: The major components named vitamin B1, vitamin B2, vitamin B6, nicotinamide and atropine sulfate in Vitamin B Complex Atropine Solution were determined by HPLC-DAD. Results: The results showed that the major components were well separated and the linear relationships were good within wide ranges by HPLC. Conclusion: The method is convenient, accurate and could be readily utilized as a quality control method for the Vitamin B Complex Atropine Solution. |
| Key words: Vitamin B Complex Atropine Solution HPLC Determination of Content |
