| 摘要: |
| 目的：探讨肺炎支原体感染与小儿支气管哮喘急性发作的关系。方法：选取我院收治的85例支气管哮喘患儿（研究组）和50例上呼吸道感染患儿（对照组）作为研究对象，对两组患儿嗜酸粒细胞、血清肺炎支原体抗体（MP-IgM）、免疫球蛋白E（IgE）及研究组患儿急性期肺功能进行检测，对检测结果进行相关性分析。结果：研究组患儿的MP-IgM阳性检出率为42.35%，高于对照组的14.00%（P<0.05）；研究组MP-IgM阳性患儿的嗜酸粒细胞、血清IgE水平均高于MP-IgM阴性患儿（P<0.05）；研究组急性期患儿MP-IgM阳性率为60.87％，缓解期患儿的阳性率为22.22％，差异有统计学意义（P<0.05）。急性期患儿MP-IgM阳性者的FEV1、FEV1％均低于阴性者（P<0.05）。支气管哮喘急性期患儿的MP-IgM阳性表达与FEV1、FEV1％均呈负相关（ｒ分别为－0.782、－0.699，P<0.05）。结论：支气管哮喘急性发作患儿多伴有肺炎支原体感染，肺炎支原体感染与小儿支气管哮喘急性发作有着密切联系。 |
| 关键词: 儿童 支气管哮喘 急性发作 肺炎支原体感染 相关性 |
| DOI：10.13407/j.cnki.jpp.1672-108X.2017.07.002 |
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| 基金项目: |
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| Relationship between Mycoplasma Pneumoniae Infection and Acute Exacerbation of Bronchial Asthma in Children |
| Ma Wenling, Ma Yufeng |
| (Dongchangfu Maternal and Chinld Health Hospital, Shandong Liaocheng 252000, China) |
| Abstract: |
| Objective: To explore the relationship between Mycoplasma pneumoniae infection and acute exacerbation of bronchial asthma in children. Methods: 85 cases of asthmatic children (study group) and 50 cases of upper respiratory tract infection children (control group) in our hospital as research subjects. Detected eosinophils and serum Mycoplasma pneumonia-immunoglobulin M (MP-IgM), immunoglobulin E (IgE) of two groups, and detected the lung function of acute phase of the study group, retrospective analysis the detect results of two groups of children. Results: MP-IgM positive rate of study group was 42.35%, it was significantly higher than control group (14.00%, P<0.05). The eosinophils and serum IgE levels in MP-IgM positive children of study group were significantly higher than the MP-IgM negative patients (P<0.05). MP-IgM positive rate in acute phase of study group was 60.87%, the positive rate of remission was 22.22%, there was a significant difference between two groups (P<0.05). In children with acute, FEV1 and FEV1% of MP-IgM positive children were significantly lower than the negative children (P<0.05). MP-IgM positive expression in acute phase of bronchial asthma children showed a negative correlation with FEV1 and FEV1% (r=-0.782, -0.699, P<0.05). Conclusion: Children with acute asthma attack usually accompanie with Mycoplasma pneumonia, mycoplasma. Mpneumoniae infection has closely linked with acute exacerbation of bronchial asthma children. |
| Key words: children bronchial asthma acute attack mycoplasma pneumoniae correlation |
