| 摘要: |
| 目的:研究不同疗程阿奇霉素治疗儿童轻症肺炎支原体肺炎的疗效差异。方法:2015年入住温州医科大学附属育英儿童医院,确诊为轻症肺炎支原体肺炎的70例患儿,随机分成短疗程组34例(使用2个疗程阿奇霉素治疗)和长疗程组36例(使用3个疗程阿奇霉素治疗),比较两组患儿临床表现、实验室指标及第2个疗程后和第3个疗程后复查胸部X 线片转归情况等。结果:短疗程组及长疗程组在入院时临床表现及实验室指标方面比较差异无统计学意义(P>0.05),具有可比性。两组患儿治疗后WBC及CRP均降至正常范围,且短疗程组与长疗程组在肺部体征好转中位时间(3 d vs 5 d)、咳嗽好转中位时间(6.4 d vs 7.3 d)比较差异均无统计学意义(P>0.05)。两组患儿分别在治疗第2疗程后及第3疗程后复查胸部X线片,两次复查胸部X线片转归比较差异无统计学意义(第2疗程后χ2=1.73,P>0.05;第3疗程后χ2=1.14,P>0.05)。两组患儿治疗期间均未出现明显不良反应,随访6个月后均未出现再次因MPP住院现象。结论:阿奇霉素短疗程组和长疗程组在治疗儿童轻症肺炎支原体肺炎疗效上差异无统计学意义,短疗程治疗更有推广价值。 |
| 关键词: 肺炎支原体肺炎 阿奇霉素 疗程 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2018.01.004 |
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| 基金项目: |
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| Azithromycin in Different Treatment Courses on Mild Mycoplasma Pneumoniae Pneumonia in Children |
| Sheng Jiangyin, Li Changchong, Zhang Hailin, Yu Lu |
| (Yuying Children's Hospital of Wenzhou Medical University, Zhejiang Wenzhou 325000, China) |
| Abstract: |
| Objective: To observe the effect of azithromycin in different treatment courses on infantile mild Mycoplasma pneumoniae pneumonia. Methods: Seventy children with mild Mycoplasma pneumoniae pneumonia who treated in Yuying Children爷s Hospital of Wenzhou Medical University in 2015 were selected. All children were divided into two groups randomly. Children in short course of treatment group were given azithromycin for two courses with 34 cases, while those in long course of treatment group were given azithmmycin for three courses with 36 cases. Clinical manifestation, laboratory indicators and the chest X﹣ray efficacy after treatment were compared between two
groups. Results: There were no significant differences on short course and long course of treatment in the clinical manifestations and laboratory indicators (P>0.05). After treatment, the count of WBC and the level of CRP in the two groups were dropped to the normal. Long course and short course of treatment in the remission time of rales in lungs (3 d vs 5 d), coughing (6.4 d vs 7.3 d) had no significant differences (P>0.05). Two groups all reexamined chest radiograph after the second period and three period course of treatment. The outcomes were with no significant differences between the two groups (P>0.05). Two groups had no adverse reactions and they were followed﹣up for 6 months, they all were not reappeared. Conclusion: Short course and long course of treatment group has no significant difference on infantile mild Mycoplasma pneumoniae pneumonia. Short course of treatment is worthy to be promoted. |
| Key words: Mycoplasma pneumoniae pneumonia azithromycin treatment course |
