| 摘要: |
| 目的:建立针对儿童的头孢曲松药物利用评价(DUE) 标准,为规范儿童抗菌药物使用提供参考。方法:参照药品说明
书、权威指南及书籍等制定头孢曲松DUE 标准并应用于临床;分析比较我院2021 年7-9 月和2022 年7-9 月使用头孢曲松的
住院病例,评价DUE 标准应用情况。结果:2022 年7-9 月的病程记录、检验指标、禁忌证、联合用药指征以及剂量和频次的符合
标准占比较2021 年7-9 月明显提高,但检验指标、联合用药指征、剂量和频次、药物相互作用方面,仍低于目标值。结论:建立
的头孢曲松儿童DUE 标准,可有效用于头孢曲松的使用评价,及时发现问题并提出整改措施,促进临床合理用药。 |
| 关键词: 儿童 头孢曲松 合理用药 药物利用评价 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2024.05.006 |
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| 基金项目: |
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| Establishment and Application of Drug Use Evaluation for Ceftriaxone in a Children’s Hospital |
| Zhang Xiaoyan, Cai Heping, Zhou Chengyue |
| (Anhui Provincial Children’s Hospital, Hefei 230051, China)) |
| Abstract: |
| Objective: To establish the drug use evaluation (DUE) for ceftriaxone in children, so as to provide reference for regulating
the use of antibiotics in children. Methods: The DUE standard for ceftriaxone was formulated according to the drug instructions,
authoritative guidelines and books, and finally applied in clinic. Inpatients treated with ceftriaxone in our hospital from Jul. to Sept.
2021 and from Jul. to Sept. 2022 were analyzed and compared to evaluate the application of DUE standard. Results: From Jul. to Sept.
2022, the compliance standards of the disease course records, test indicators, contraindications, indications of drug combination, and
dose and frequency increased significantly compared with those from Jul. to Sept. 2021, yet the test indicators, indications of drug
combination, dose and frequency, and drug interactions were still lower than the target value. Conclusion: The established DUE
standard for ceftriaxone in children can be effectively used for the evaluation, timely detection of problems and rectification measures,
and promotion of rational drug use in clinic. |
| Key words: children ceftriaxone rational drug use drug use evaluation |
