| 摘要: |
| 目的：本研究通过检测血清降钙素原（PCT）水平的变化，探讨其在小儿社区获得性肺炎（CAP）诊治中的临床意义。方法：选取我院97例确诊为CAP的患儿，分为细菌感染性CAP组（47例，A组），非细菌感染性CAP组（50例，B组），另选取我院门诊体检健康儿童作为健康对照组（45例，C组），检测各组患儿治疗前与治疗后以及A组内重症感染者（D组）与非重症感染者（E组）血清PCT水平并比较其变化。结果：（1）A组PCT水平显著高于B组及C组（P<0.05）。（2）A组及B组C反应蛋白水平（CRP）、白细胞（WBC）计数显著高于C组（P<0.05），A组与B组CRP、WBC比较差异无统计学意义（P>0.05）。（3）D组PCT水平显著高于E组（P<0.05）。（4）治疗后A组PCT、CRP水平以及WBC计数较治疗前明显下降，治疗后B组CRP水平以及WBC计数较治疗前明显下降，差异均有统计学意义（P<0.05）。结论：血清PCT对小儿细菌感染性CAP与非细菌性感染CAP鉴别诊断有指导意义，且对感染严重程度有一定评估作用。 |
| 关键词: 降钙素原 社区获得性肺炎 C反应蛋白 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2016.06.004 |
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| 基金项目: |
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| Clinical Value of Serum Procalcitonin for Pneumonia in Children |
| Lu Yuzhou, Liu Xiaowei |
| (Qinzhou Fist People’s Hospital of Guangxi, Guangxi Qinzhou 535000, China) |
| Abstract: |
| Objective: To research the clinical value of procalcitonin (PCT) in children’s community-acquired pneumonia (CAP). Methods: Patients were divided into three groups: in bacteria CAP group (n=47, group A), non-bacteria CAP group (n=50, group B) and normal control group (n=45, group C ). Serum PCT was measured before and after treatment in all groups. Results: (1) Serum PCT in group A was higher than that of group B and group C (P<0.05). (2) The level of CRP and WBC in group A and group B were higher than those of group C (P<0.05). There was no significant difference group A and group B (P>0.05). (3) The level of PCT and CRP in severe infection group were higher than those of non-severe infection group (P<0.05). (4) The level of PCT, CRP and WBC were significantly lower in group A after treatment (P<0.05), while the level of CRP and WBC were significantly lower in group B after treatment (P<0.05). Conclusion: Serum PCT was significant for clinical diagnosis, and it can reflect the severity of disease. |
| Key words: Procalcitonin Community-acquired pneumonia C-reactive protein |
