| 摘要: |
| 目的：调查我院儿科药物不良反应（ADR）的发生情况，探讨其防控措施。方法：选取2012年9月至2013年8月我院儿科接诊的患儿1 582例，安排临床护士集中监测ADR发生情况并填写《ADR监测表》，对上报的ADR进行统计分析。结果：总体ADR发生率为19.2%（303/1 582）。静脉给药ADR发生率（74.2%）高于其他给药方式；1~3岁患儿ADR发生率（32.8%）高于其他年龄段患儿；夏季ADR发生率（29.6%）高于其他季节；抗生素ADR发生率（80.7%）高于其他类别药物。结论：儿科ADR的发生与给药方式、年龄、季节、药物类别等因素有关，其防控重点应是加强ADR监测，提高合理用药水平。 |
| 关键词: 儿科 药物不良反应 调查 防控 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2016.12.015 |
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| 基金项目: |
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| The Occurrence and Prevention of Adverse Drug Reactions in Pediatric Medicine in Our Hospital |
| Jia Guiyun, Liu Yanfen, Chang Mingxing, Liu Jingwen |
| (Pinggu Hospital of Beijing, Beijing 101200, China) |
| Abstract: |
| Objective: To investigate the occurrence of drug adverse reactions in pediatric department and to investigate the preventive and treatment measures. Methods: 1,582 children cured in pediatric department from September 2012 to August 2013 with clinical data were selected as the research object, arrange clinical nurse centralized monitoring ADR occurrence and fill out the “ADR monitoring table”, and monitor the drug adverse reactions. Results: The incidence of adverse reactions was 19.15% (303/1,582). The incidence of adverse drug reactions caused by intravenous administration was higher than that of other drugs, and account for 74.2% of the total adverse reactions. The incidence of adverse drug reactionsin ages 1 to 3 was higher than that of other ages, and account for 35.1% of the total adverse reactions. The number of adverse reactions in winter accounted for 37.4% of total cases, the proportion of the total cases was the largest in the four seasons. the proportion of adverse reactions caused by antibiotics was the largest, and reached 70.9%. Conclusion: The occurrence of adverse drug reactions in pediatrics was related with the age, season, drug type and other factors, and its prevention and treatment should be to strengthen the monitoring of adverse drug reactions and improve the level of rational drug use. |
| Key words: pediatrics adverse drug reactions investigation prevention and treatment |
