| 摘要: |
| [摘要]目的：探讨磷酸铝凝胶预防静脉滴注阿奇霉素所致胃肠道反应的效果。方法：选取2016年1月至12月在我院静脉滴注阿奇霉素的支原体肺炎（MPP）患儿146例，随机分成治疗组和对照组，治疗组83例在静脉滴注阿奇霉素前30 min口服磷酸铝凝胶1次，对照组63例不予口服磷酸铝凝胶，观察两组患儿胃肠道反应发生情况。结果：治疗组总的胃肠道反应发生率为30.1%，对照组总的胃肠道反应发生率为81.0%，两组比较差异有统计学意义（χ2＝37.08，P<0.01）。结论：口服磷酸铝凝胶可有效预防儿童静脉滴注阿奇霉素所致的胃肠道反应。 |
| 关键词: 磷酸铝凝胶 阿奇霉素 胃肠道反应 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2018.06.007 |
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| 基金项目: |
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| Aluminum Phosphate Gel in Preventing Gastrointestinal Reactions Caused by Intravenous Azithromycin in Children |
| Chen Jieru, Guo Yi |
| (Wuxi No.2 People’s Hospital, Jiangsu Wuxi 214002, China) |
| Abstract: |
| [Abstract] Objective: To investigate the clinical efficacy of aluminum phosphate gel in preventing gastrointestinal reactions caused by intravenous azithromycin in children. Methods: One hundred and forty-six children with Mycoplasma Pneumoniae pneumonia accepting intravenous azithromycin therapy from Jan. to Dec. 2016 were randomly divided into treatment group (n=83) and control group (n=63). The treatment group was orally administrated with aluminum phosphate gel 30 minutes before intravenous azithromycin therapy, while the control group did not treated with aluminum phosphate gel. Gastrointestinal reactions of two groups were observed. Results: The incidence of gastrointestinal reactions of treatment group was 30.1%, yet the control group was 81.0%, the difference was statistically significant(χ2＝37.08，P<0.01). Conclusion: Aluminum phosphate gel can prevent gastrointestinal reactions caused by intravenous azithromycin in children. |
| Key words: aluminum phosphate gel azithromycin gastrointestinal reactions |
