| 摘要: |
| [摘要]目的：评价热毒宁注射液在儿科超说明用药情况，为儿童安全合理应用热毒宁注射液和临床管理提供参考。方法：抽取我院儿科2016年使用热毒宁注射液的出院病历，对患儿的基本情况、给药剂量、用药频次、配制浓度、用药疗程等信息进行统计分析。结果：超说明书用药患儿年龄：<3岁占11.07%，3~5岁占37.37%，6~10岁占48.10%，11~13岁占3.46%；超说明书用药类型：超疗程用药占69.81%，单次给药剂量低于治疗剂量22.01%，配制浓度过低占7.55%。结论：热毒宁注射液在儿科存在超说明书用药情况，必须加强管理，促进其规范使用，保障患儿用药安全。 |
| 关键词: 热毒宁注射液 儿科 合理用药 超说明书用药 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2018.06.014 |
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| 基金项目: |
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| Evaluation of Off-Label Drug Use of Reduning Injection in Pediatric |
| Liu Na1, Hou Jiqiu2, Xiao Jinbao2, Wang Li1, Yan Zaihua1 |
| (1. Tonghua Central Hospital, Jilin Tonghua 134000, China; 2. The Second Hospital of Jilin University, Jilin Changchun 131000, China) |
| Abstract: |
| [Abstract] Objective: To evaluate the off-label drug use of Reduning injection in pediatric, so as to provide reference for the rational use and clinical management of Reduning injection on children. Methods: Discharged medical records with application of Reduning injection in pediatric were extracted and analyzed in terms of patients’ general information, dosage, frequency of administration, formulation concentration, treatment course. Results: Of the child patients’ applied with Reduning injection, 11.07% were <3 years old, 37.37% were aged between 3 to 5, 48.10% were aged between 6 to 10, 3.46% were aged between 11 to 13; the types of off-label drug use included 69.81% of over-course of treatment, 22.01% of lower administration dose than therapeutic dose, and 7.55% of over lowering formulation concentration. Conclusion: Off-label drug use of Reduning injection exists in pediatric, which should be given strengthened management, with its standardized use promoted and the safety of children’s medication ensured. |
| Key words: Reduning injection pediatrics rational drug use off-label drug use |
