| 摘要: |
| 目的:为采用支气管肺泡灌洗术治疗儿童重症肺炎提供基础研究参考资料。方法:选取2014年9月至2017年9月在我院就诊的重症肺炎患儿67例,根据治疗方法不同分为研究组(采用常规治疗方法+支气管肺泡灌洗术)34例和对照组(采用常规治疗方法)33例,检测患儿血清白细胞、C反应蛋白和降钙素水平,评价治疗效果并比较两组患儿的预后及并发症发生情况。结果:研究组患儿治愈率和总有效率分别为52.94%和91.18%,均高于对照组的24.24%和66.67%(P均<0.05);住院时间、咳嗽消失时间、抗生素使用时间、啰音消失时间、胸部X 线片阴影消退时间、发热时间均短于对照组(P均<0.05)。治疗后两组患儿血清白细胞、C反应蛋白和降钙素水平均较治疗前下降,且研究组均低于对照组(P均<0.05)。两组患儿发生发热、一过性低氧血症、咳嗽加重的比例比较差异均无统计学意义(P均>0.05),但研究组患儿发生呼吸急促的比例低于对照组(P<0.05)。结论:支气管肺泡灌洗术对儿童重症肺炎具有良好的治疗效果,且并发症较少。 |
| 关键词: 儿童 重症肺炎 支气管肺泡灌洗术 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2018.07.009 |
|
| 基金项目:佛山市医学类科技攻关项目,编号2015AB0401。 |
|
| Bronchoalveolar Lavage for Severe Pneumonia in Children |
| Pan Zhiwei, Lin Yehui, Wen Yongzhao |
| (Foshan Women and Children Hospital, Guangdong Foshan 528000, China) |
| Abstract: |
| Objective: To provide basic research references for bronchoalveolar lavage for severe pneumonia in children. Methods: Sixty-seven children with severe pneumonia admitted into Sept. 2014 to Sept. 2017 were extracted to be divided into research group (conventional treatment + bronchoalveolar lavage) with 34 cases and control group (conventional treatment) with 33 cases. Serum leukocytes, C-reactive protein and calcitonin levels were detected, therapeutic effects were evaluated, prognosis and complications of two groups were compared. Results: The cure rate and total efficiency of research group were 52.94% and 91.18% respectively, higher than those of control group 24.24% and 66.67% (P<0.05). The length of stay, disappearance time of cough, application time of antibiotics, disappearance time of rales, disappearance time of chest X-ray shadow and time of fever of research group were all shorter than those of control group (P<0.05). After treatment, the serum leukocytes, C-reactive protein and calcitonin levels of both groups were decreased compared with before treatment, and the research group was lower than the control group (P<0.05). There was no statistically significant difference in the incidence of fever, transient hypoxemia, and worsening of cough in two groups (P>0.05), yet the rate of tachypnea in research group was lower than that in control group (P<0.05). Conclusion: Bronchoalveolar lavage has significant therapeutic effects in children with severe pneumonia with fewer complications. |
| Key words: children severe pneumonia bronchoalveolar lavage |
