| 摘要: |
| 目的：探讨临床药师在新生儿洋葱伯克霍尔德菌感染治疗中的作用。方法：回顾性分析临床药师参与1例左氧氟沙星治疗新生儿洋葱伯克霍尔德菌感染的病例。结果：临床药师通过对左氧氟沙星用于新生儿感染的风险和益处进行评估，参与抗感染方案的调整，经过综合治疗患儿呼吸较前好转，体温恢复正常，病情改善。结论：在充分评估风险获益后，氟喹诺酮类药物可用于治疗危及生命或难以治疗的感染儿童，有利于降低儿科患者洋葱伯克霍尔德菌重症感染的致死率。 |
| 关键词: 左氧氟沙星 洋葱伯克霍尔德菌 新生儿 |
| DOI：10.13407/j.cnki.jpp.1672-108X.2020.11.010 |
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| 基金项目:河南省科技攻关项目,编号182102310422。 |
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| Clinical Analysis and Literature Review of Levofloxacin in the Treatment of Neonatal Burkholderia Cepacia Infection |
| Sun Chong, Li Yan, Ma Shuli |
| (Children’s Hospital Affiliated of Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Henan Zhengzhou 450000, China) |
| Abstract: |
| Objective: To probe into the role of clinical pharmacists in anti-infective treatment of neonatal Burkholderia cepacia infection. Methods: Retrospective analysis was performed on clinical pharmacists’ participation of levofloxacin in the treatment of neonatal Burkholderia cepacia infection. Results: Clinical pharmacists assessed the risks and benefits of levofloxacin for neonatal infection, and participated into the adjustment of anti-infective regimens. After comprehensive treatment, the child’s respiration was better than before, and the body temperature returned to the normal state. Conclusion: After fully assessing the risks and benefits, fluoroquinolones can be used to treat life-threatening or difficult-to-treat children with infections, which will help to reduce the mortality of pediatrics with severe Burkholderia cepacia infection. |
| Key words: levofloxacin Burkholderia cepacia neonates |
