| 摘要: |
| [摘要]目的：调查分析儿科门诊超说明书用药情况，为儿科合理用药提供参考。方法：随机抽取我院2019年7-12月儿科门诊处方，根据药品说明书判断其用药是否超说明书，统计分析超说明书用药类型、患儿年龄段及药品种类分布情况。结果：共抽取门诊处方1 200张，含3 285条用药医嘱。超说明书用药处方比例为29.42%，超说明书用药医嘱比例为18.60%。超说明用药类型主要是无儿童用药信息（45.17%）和超适应证用药（24.39%）。超说明书用药主要发生在婴幼儿期（32.25%）和学龄前期（21.27%），药物类别以呼吸系统用药（27.17%）、中成药（24.01%）和抗感染药（22.92%）为主。结论：儿科门诊超说明用药较普遍，国家应制定相关法规，医院应加强超说明书用药的监管，以保障儿童用药的安全合理。 |
| 关键词: 儿科 超说明书 合理用药 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2022.05.007 |
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| 基金项目: |
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| Investigation and Analysis on Off-Label Drug Use in Pediatric Outpatients of a Hospital |
| Liu Ting, Yu Jingjie |
| (The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710004, China) |
| Abstract: |
| [Abstract] Objective: To investigate and analyze the off-label drug use in the pediatric outpatients, so as to provide reference for rational drug use in pediatrics. Methods: Pediatric outpatient prescriptions in our hospital from Jul. to Dec. 2019 were randomly extracted to determine whether off-label drug use was used according to drug instructions, and the types of off-label drug use, age of children and distribution of drug types were statistically analyzed. Results: A total of 1,200 outpatient prescriptions were selected, including 3,285 medical orders. The proportion of off-label drug use prescriptions was 29.42%, and the proportion of off-label drug use medical orders was 18.60%. The main types of off-label drug use were no information on drug use for children (45.17%) and off-label indication (24.39%). Off-label drug use mainly occurred in infancy (32.25%) and preschool age (21.27%), and the drug categories were mainly respiratory system drugs (27.17%), Chinese patent medicines (24.01%) and anti-infective drugs (22.92%). Conclusion: Off-label drug use is common in pediatric outpatients, relevant laws and regulations should be formulated and supervision of off-label drug use should be strengthened in hospitals to ensure the safety and rationality of drug use in children. |
| Key words: pediatrics off-label rational drug use |
