| 摘要: |
| 目的：为静脉用药调配中心（PIVAS）非整支粉针剂的精准配制提供合理的稀释溶媒量参考。方法：通过模拟实际药品稀释过程，采用精确的测量方法，通过统计分析得出合理的稀释溶媒量。结果：总结出我院常用54种粉针剂的稀释溶媒量，得出如下规律：精准配制后，剂量<0.40 g的粉针剂药液增量为0，剂量0.40~0.60 g药液增量0.3 mL，剂量1.00~1.20 g药液增量0.6 mL，剂量1.50~2.25 g药液增量1.0 mL。结论：粉针剂的精准稀释有一定的规律，通过引入相对误差分析，能得出更合理的稀释溶媒量，有利于儿童医院PIVAS的精准调配 |
| 关键词: 静脉用药调配中心 非整支粉针剂 精准稀释 |
| DOI：10.13407/j.cnki.jpp.1672-108X.2022.03.008 |
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| 基金项目:郴州市第一人民医院院级基金项目,编号ZZ201713 |
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| Precise Dilution of Non-Integral Powder Injection in Pharmacy Intravenous Admixture Services of a Children’s Hospital |
| Jiang Qianqiu, Zhong Wenting, Xiao Liangying, Zhang Tiantian |
| (Children’s Hospital, the First People’s Hospital of Chenzhou, Hunan Chenzhou 423000, China) |
| Abstract: |
| Objective: To provide reference for rational amount of dilution solvent for precise dispensing of non-integral power injection in pharmacy intravenous admixture services (PIVAS). Methods: By simulating the actual process of drug dilution and using accurate measurement methods, the rational amount of dilution solvent was obtained through statistical analysis. Results: The amount of dilution solvent for 55 kinds of powder commonly used in our hospital was summarized. The following rules were obtained: the liquid volume of powder injection drugs with dose <0.40 g increased by 0 after dispensing; the liquid volume of powder injection drugs with dose from 0.40 to 0.60 g increased by 0.3 mL after dispensing; the liquid volume of powder injection drugs with dose from 1.00 to 1.20 g increased by 0.6 mL after dispensing, the liquid volume of powder injection drugs with dose from 1.50 to 2.25 g increased by 1.0 mL after dispensing. Conclusion: The precise dilution of powder injection has a certain rule. By introducing relative error analysis, a more rational amount of dilution solvent can be obtained, which is conducive to the precise dispensing in PIVAS of the children’s hospital. |
| Key words: pharmacy intravenous admixture services non-integral power injection precise dilution |
