| 摘要: |
| 目的:探讨利妥昔单抗治疗儿童激素依赖型肾病综合征的药学监护要点。 方法:以 1 例利妥昔单抗治疗的儿童激素依赖型肾病综合征为例,临床药师对利妥昔单抗的使用进行全程药学监护。 结果:临床药师从利妥昔单抗的使用剂量、不良反应的预防、肺孢子虫感染的预防等方面提出了药学建议,提高了患儿用药的安全性和有效性。 结论:临床药师作为临床治疗团队
中的一员,在临床个体化药物治疗中发挥着积极作用。 |
| 关键词: 利妥昔单抗 肾病综合征 药学监护 |
| DOI：10. 13407/ j. cnki. jpp. 1672-108X. 2023.10.003 |
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| 基金项目:上海市“医苑新星”青年医学人才培养资助计划,编号 SHWSRS[2020]087 |
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| Pharmaceutical Care for Rituximab in the Treatment of Children with Steroid-Dependent Nephrotic Syndrome by Clinical Pharmacists |
| Yang Yuzhu, Xie Ting, Yang Qiaoling, Sun Huajun, Liu Hongxia |
| (Children’s Hospital of Shanghai, Children’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200062, China) |
| Abstract: |
| Objective: To explore the pivotal points of pharmaceutical care for rituximab in the treatment of children with steroiddependent nephrotic syndrome. Methods: Taking a child with steroid-dependent nephrotic syndrome treated with rituximab as an example, clinical pharmacists provided comprehensive pharmaceutical care throughout the use of rituximab. Results: Clinical pharmacists provided pharmaceutical recommendations regarding the dosage of rituximab, prevention of adverse drug reactions, and prevention of Pneumocystis jirovecii infection, which improved the safety and efficacy of children’s medication. Conclusion: As members of the clinical treatment team, clinical pharmacists play an active role in individualized drug therapy in clinical practice. |
| Key words: ]rituximab nephrotic syndrome pharmaceutical care |
