| 摘要: |
| 目的:探讨羟考酮联合舒芬太尼在小儿扁桃体腺样体切除术的应用价值。 方法:选择全身麻醉下行择期扁桃体腺样体切除的患儿 80 例,按随机数表法分为舒芬太尼组(S 组)和羟考酮+舒芬太尼组(O+S 组)各 40 例。 监测麻醉诱导前(T0 )、气管插管时(T1 )、拔除气管导管时(T2 )、拔管后 5 min(T3 )、离开麻醉后监测治疗室(PACU)时(T4 )的心率和平均动脉压;记录 T3 及T4 患儿疼痛行为量表(FLACC)评分及儿童麻醉苏醒期躁动量表(PAED)评分。 记录患儿麻醉诱导时呛咳、在 PACU 躁动、恶心呕吐、呼吸抑制等不良反应发生率。 结果:S 组患儿 T1 、T2 时及 O+S 组患儿 T1 时的心率和平均动脉压较 T0 时升高(P<0. 05);O+S 组患儿 T2 时心率和平均动脉压低于 S 组(P<0. 05)。 O+S 组患儿 T3 、T4 时 FLACC 评分及 T3 时 PAED 评分低于 S 组,诱导时呛咳、术后躁动的发生率低于 S 组(P<0. 05)。 结论:与单用舒芬太尼相比,小儿扁桃体腺样体切除术中采用羟考酮 0. 2 mg / kg+舒芬太尼 0. 2 μg / kg 联合诱导麻醉,可提高术后镇痛满意度,减少呛咳及术后躁动等不良反应的发生。 |
| 关键词: 羟考酮 舒芬太尼 儿童 扁桃体腺样体切除术 |
| DOI：10.13407/j.cnki.jpp.1672-108X.2023.09.008 |
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| 基金项目: |
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| Effects of Oxycodone Combined with Sufentanil on Tonsillectomy and Adenoidectomy in Children |
| Duan Chenxia1, Zhang Zuoliang1, Gao Xiuxiu1, Chen Yi1, Wei Lei1, Zhang 2 |
| (1. Suzhou Hospital Affiliated to Nanjing Medical University, Jiangsu Suzhou 215002, China; 2. Nanjing Children’s Hospital, Nanjing 210000, China) |
| Abstract: |
| Objective: To probe into the application value of oxycodone combined with sufentanil on tonsillectomy and adenoidectomy in children. Methods: A total of 80 children with elective tonsillectomy and adenoidectomy under general anesthesia were extracted to be divided into the sufentanil group (S group) and oxycodone+sufentanil group (O+S group) via the random number table method, with 40 cases in each group. Heart rate and mean arterial pressure were detected before induction of anesthesia ( T0 ), during endotracheal
intubation (T1 ), at the time of endotracheal intubation removal (T2 ), 5 minutes after extubation (T3 ), and at the time of leaving post anesthesia care unit (PACU, T4 ). Pediatric pain behavior scale (FLACC) score and pediatric anesthesia emergence delirium (PAED) score at T3 and T4 were recorded. The incidence of cough, restlessness in PACU, nausea and vomiting, respiratory depression and other adverse drug reactions during anesthesia induction were recorded. Results: Compared with T0 , the heart rate and mean arterial pressure of the S group at T1 and T2 and O+S group at T1 increased significantly (P<0. 05). The heart rate and mean arterial pressure of O+S group at T2 were significantly lower than those of the S group (P<0. 05). The FLACC scores at T3 and T4 and PAED scores at T3 in the O+S group were lower than those in the S group, the incidence of cough during induction and postoperative restlessness was lower than that in the S group (P<0. 05). Conclusion: Compared with sufentanil alone, oxycodone 0. 2 mg / kg+ sufentanil 0. 2 μg / kg induced anesthesia during tonsillectomy and adenoidectomy in children can improve the satisfaction of postoperative analgesia and reduce the
occurrence of adverse drug reactions such as cough and postoperative restlessness. |
| Key words: oxycodone sufentanil children tonsillectomy and adenoidectomy |
