| 摘要: |
| 目的:总结自动粉剂分包机的使用经验,探讨其应用价值。方法:选取3 种常需分剂量的药品分别进行人工和机器(自
动粉剂分包机)分剂量至1/ 5、1/ 8、1/ 10 各3 批,每批各取30 包精密称量并记录,计算并比较各批的相对标准偏差(RSD) 与合
格率。结果:粉剂分包机分剂量合格率高于人工分剂量(P<0. 05)。其中,分包总量>3 g 的1/ 5 粒熊去氧胆酸胶囊的分包机分
剂量RSD 低至3. 26%~4. 21%,合格率达到100%。结论:自动粉剂分包机分剂量大大提高了分剂量的准确度,用好自动粉末分
包机对推动儿童精准分剂量调剂工作的发展至关重要。 |
| 关键词: 儿童 分剂量 自动粉剂分包机 精准用药 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2024.04.008 |
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| 基金项目: |
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| Application of Automatic Powder Dispensation Machine in Increasing Accuracy of Pharmaceutical Dose-Splitting |
| Xiong Yilan, Chen Zebin, Liu Wei |
| ((Shenzhen Children’s Hospital, Guangdong Shenzhen 518026, China)) |
| Abstract: |
| Objective: To summarize the application experiences of automatic powder dispensation machine, and probe into the
application value. Methods: Three kinds of drugs that often need to be split for required dose were divided into 3 batches by manual and
machine (automatic powder dispensation machine) to 1/ 5, 1/ 8 and 1/ 10 respectively, and 30 packets of each batch were accurately
weighed and recorded. The relative standard deviation (RSD) and qualified rate of each batch were calculated and compared. Results:
The qualified rate of dose-splitting by automatic powder dispensation machine was higher than that of manual dose-splitting (P<0. 05).
The RSD of dose-splitting of 1/ 5 ursodeoxycholic acid capsules by automatic powder dispensation machine with a total weight >3 g was
reduced to 3. 26% to 4. 21%, and the qualified rate reached 100%. Conclusion: The accuracy of dose-splitting has been greatly
improved by automatic powder dispensation machine. The application of automatic powder dispensation machine is critical to the
advancement of accurate dose-splitting for children. |
| Key words: children dose-splitting automatic powder dispensation machine precise medication |
