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欧洲药学监护联盟分类系统在儿科用药相关问题中的探索和实践
钱巧1,张宁1,张凤怡1,马红1,丁玲1,刘玲2
0
(1. 南京医科大学第四附属医院,南京 210031;2. 宿迁市第一人民医院,江苏宿迁 223800)
摘要:
目的:探索欧洲药学监护联盟(PCNE)分类系统在儿科用药相关问题中的应用。 方法:选取 2021 年 11 月-2022 年 10 月在南京医科大学第四附属医院儿科住院治疗的患儿为研究对象,专职临床药师全程参与查房并进行医嘱审核,采用 PCNE 分类系统(9. 1 版)评估患儿出现的药物相关问题(DRPs),并对发生 DRPs 的类型、原因、干预方案、干预方案的接受程度及 DRPs 状态等进行分析。 结果:本研究共纳入 1 184 例患儿,其中专职临床药师发现 304 例患儿在住院治疗期间存在不同程度的 DRPs,总计 336 例。 DRPs 类型中与治疗有效性相关的问题 175 例(52. 08%),与治疗安全性相关的问题 117 例(34. 82%);药物剂量过低和药物疗程过长为 DRPs 发生的主要原因;实际干预 292 例,干预成功率为 86. 90%。 结论:PCNE 分类体系的引入能够提升临床药师发现和解决 DRPs 的能力,将 PCNE 分类系统作为契机,建立完善的药学监护系统,精确分析 DRPs,促进合理用药,保障对儿童的用药安全。
关键词:  欧洲药学监护联盟分类系统  儿科用药  药学监护
DOI:10.13407/j.cnki.jpp.1672-108X.2024.06.003
基金项目:
Exploration and Practice of Pharmaceutical Care Network Europe Classification System in PediatricMedication-Related Issues
Qian Qiao1, Zhang Ning1, Zhang Fengyi1, Ma Hong1, Ding Ling2, Liu Ling3
(1. The Fourth Affiliated Hospital of NanjingMedical University, Nanjing 210031, China; 2. Suqian First People’s Hospital, Jiangsu Suqian 223800, China)
Abstract:
Objective: To probe into the application of Pharmaceutical Care Network Europe (PCNE) classification system in pediatricmedication-related issues. Methods: Children hospitalized in pediatrics of the Fourth Affiliated Hospital of Nanjing Medical Universityfrom Nov. 2021 to Oct. 2022 were selected as the research subjects. Professional clinical pharmacists participated into the ward roundand reviewed the medical orders. The PCNE classification system ( version 9. 1) was used to evaluate the occurrence of drug-relatedproblems ( DRPs) in children, and the types, causes, intervention programs, acceptance of intervention programs of DRPs wereanalyzed. Results: A total of 1,184 children were enrolled, professional clinical pharmacists found 304 children with different degrees ofDRPs ( 336 cases) during hospitalization. There were 175 questions ( 52. 08%) related to treatment efficacy and 117 questions(34. 82%) related to treatment safety in the types of DRPs. The main reasons for the occurrence of DRPs were low dosage of drugs andlong treatment course in the type of causes. There were 292 actual interventions, with a success rate of 86. 90%. Conclusion:Introduction of PCNE classification system can improve the ability of clinical pharmacists to find and solve DRPs, and PCNEclassification system can be used as an entry point to establish the perfect pharmaceutical monitoring system, accurately analyze DRPs,promote rational drug use, and ensure the safety of drug use for children.
Key words:  ]Pharmaceutical Care Network Europe classification system  pediatric medication  pharmaceutical care

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